Nasopharyngeal carcinoma (NPC) is a human malignancy with a distinct geographical and racial distribution particularly in regions such as North Africa, Southeast Asia and China, affecting up to 129,000 individuals worldwide and its mortality rate reaching up to 56%. Asiatic acid (AA) is one of the phytochemical constituting the major compounds found in the herbal plant, C. asiatica, AA has been…
Dengue virus is the most prevalent mosquito-borne Flavivirus and is known to cause dengue hemorrhagic fever. Currently, there are no specific anti-dengue treatments or any licensed vaccine available to treat or prevent the disease, bringing dengue incidence to increase up to 30-fold in the past few decades. To stop the increasing incidence, dengue eradication programs have leaned towards vector…
"Chemotherapy is the most widely used cancer treatment, however, due to the lack of specificity to tumor cells, progression of drug resistance, and undesirable side effects produced by some chemotherapeutic, the discovery for novel anti-cancer drugs with fewer side effects with greater therapeutic efficiency is still a priority of cancer research. The major source of anti-cancer compounds is n…
Glioma is a type of cancer which arises from cells of glial origins. Glioma represents over 80% of all malignant primary neoplasms occurring in the brain and central nervous system. To date, the treatment of glioma is still limited to radiotherapy, surgery and Temozolomide. Therefore, survival rates of glioma still varies greatly between the many types of glioma with glioblastoma mult iforme—…