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Elucidating the Use of Epigenetic Drugs for Breast Cancer
Epigenetic modulator or epigenetic drug has shown promising potential as cancer therapeutic agents. In prostate cancer, inhibition of a histone methyltransferase (HMT) is able to induce IFN-JAK-STAT-mediated cell death. Previous RNA microarray data has shown that I3, an HMT inhibitor, and TSA, an HDAC inhibitor, treatment can upregulate various IFN-related genes. I3 and TSA were treated to vari…
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- BM 19-008
The Association Between Mitochondrial DNA Copy Number (MTDNA-CN) and Relativr…
Mitochondrial DNA copy number (mtDNA-CN) and relative telomere length (RTL) are promising biomarkers to have a better understanding on the general health of individuals that is correlated with diet, lifestyle, and consequently the general health status. In Indonesia, the Punans live in various part of Kalimantan, including in North Kalimantan, such as in Respen Tubu, Long Sule, and Sajau Benau.…
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- BT 19-011
Constructing and Cloning of Pegfp-N1 Vector Containing Turncated RPGRIP1L C2 …
Primary cilia is an antenna like organelle that functions as signal transmitter in eukaryotic cells. RPGRIP1L is one of the protein that is located on the primary cilia, which plays an important role in controlling cellular signaling, assembling the ciliary base, and controlling autophagy. RPGRIP1L is composed of 3 main domains, namely Coiled-coil, C2, and RIDL domain. Among those domains of RP…
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- BT 19-001
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