A preliminary antimicrobial assay showed the antimicrobial activity of P. acidilactici but the SDS-PAGE did not reveal pediocin, an antimicrobial peptide produced by Pediococcus strain. The efficient downstream processing of P. acidilactici fermentation is studied to analyze pediocin. This research is conducted to assess the compatibility of different methods in concentrating pediocin in th…
Non-small-cell lung cancer (NSCLC) comprises the majority of lung cancer about 75-80%, and a quarter of NSCLC cases have mutations in the epidermal growth factor receptor (EGFR) gene. Adenocarcinomas of the lung harboring the L858R mutation in exon 21 have proven to be more adverse in terms of prognosis than exon 19 mutations. Therefore, developing highly sensitive and selective methods to …