Thesis

Risk Assessment of Ochratoxin A (OTA) in Indonesia from Arabica Coffee (Coffea arabica) Based Consumption using the Margin of Exposure Approach

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Indonesia is a major coffee producer with government initiatives targeting the increased
demand for Arabica coffee (Coffea arabica). However, Indonesia is a tropical country, which is ideal for
the growth of Ochratoxin A (OTA) producers like Aspergillus and Penicillium. OTA is a food safety risk
due to its potential for nephrotoxicity and carcinogenicity at high exposure levels. There is still limited
study assessing the OTA occurrence in Indonesian Arabica coffee and the associated health risks. This
study aims to collect OTA contamination levels in West Java Arabica coffee samples using LC-MS-MS
and determine the safe range of coffee consumption rate using Margin of Exposure (MoE) approach.
The results showed undetected OTA levels in all of the samples. The level of MOE in Arabica coffee was
below 10.000 and the limit of detection (0.886 ng/g) in this study was below the maximum limit set by
BPOM (5 ng/g). Moreover, there were significant differences in the physicochemical properties
between the samples. Group of people with a high consumption rate (>3 cups per day) is posed to the
highest risk of OTA exposure. Safety precautions are recommended in this study, including lowering
coffee consumption rate to 1 cup daily with assumption of each cup consisting of 15 grams of coffee
beans. Moreover, proper pre- and post-harvest and storage handling of coffee beans is recommended
to prevent the ochratoxin-producing fungal growth. It would be of interest to conduct an extended risk
assessment of OTA in Indonesian coffee beans for public health.

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Availability

Detail Information

Series Title

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Call Number

FT 24-012

Publisher

i3L, Jakarta : i3L Press., 2024

Collation

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Language

English

ISBN/ISSN

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Classification

NONE

Content Type

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Media Type

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Carrier Type

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Edition

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Subject(s)

Indonesia
Arabica Coffee
Exposure
Ochratoxin A
Risk Analysis

Specific Detail Info

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Statement of Responsibility

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