In Silico and In Vitro Assessment of Coriandrum sativum Extract Potential for…

Non-small cell lung cancer (NSCLC) is the most prevalent type of lung cancer, accounting for 85% of cases of lung cancer. NSCLC is commonly treated with cisplatin, however, NSCLC develops resistance to cisplatin via several mechanisms, which reduces treatment efficacy and becomes a major challenge in its treatment. Several plant extracts have been researched as potential anticancer, includi…

Cytotoxicity For Zn-Sr Cosubstituted Hydroxypatite

Edition

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ISBN/ISSN

Intern 018-2024

Collation

x, 24 p. : ill. ; 30 cm.

Series Title

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Call Number

BM-005

The in Vitro Investigation of Methanolic Carica Papaya Leaf Extract as an Ant…

Pseudomonas aeruginosa is a significant opportunistic pathogen causing healthcare-associated infections (HAI)worldwide, its ability to form biofilms contributes to antibiotic resistance, resulting in the increased difficulty for treatment, thus finding a new therapeutic approach is crucial.

Assessing The Cytotoxic Effect of Capsicum annuum extract on Cervical Cancer

Capsicum annuum, or chili pepper, is known from traditional medicine to have anti-tumor properties. Recent researches isolated to compound responsible to be Capsaicin, with few researches opposing this notion. Since there are some disagreements as to the validity of this claim, it is important that further tests need to be conducted to prove or disprove the point. Hence, this thesis aimed to…

Investigation of the Antifungal and Anti-inflammatory Properties of Alpinian …

Candida albicans is a yeast that resides on the human skin, however it can become an opportunistic pathogen when the immune system is compromised or there are imbalances in the microenvironment. This microorganism can cause candidiasis which is able to cause high mortality rates in especially immunocompromised patients. Treating this infection is highly difficult due to similarities in stru…

Oncolytic Virus Treatment Strategies Against Liver Cancer

Hepatocellular carcinoma (HCC) poses a significant challenge in clinical management due to late-stage diagnosis and limited curative interventions. The imperative to develop more efficacious therapeutic approaches for HCC underscores the exploration of oncolytic virotherapy, an innovative treatment modality exhibiting promising antitumor properties. Among potential oncolytic vectors, the measle…

Investigating Isoflavone-adaptation Synthetic Compounds For Treating Skin Inf…

Psoriasis is an autoimmune skin disorder that has impacted the global population from children to adults. Psoriasis is characterized by unusual proliferation of keratinocytes, leading to itchy, bleeding, scaly, and red lesions due to increased immune system activity. Existing topical treatments often result in side effects, emphasizing the necessity for advanced drug discovery in managing psori…

Prediction of T-Cell and B-Cell Epitopes From Protein Allergen Tropomysin Tha…

hellfish allergy is one of the highest prevalence allergies in the world, accounting for 7.7% of the population including Indonesia. Thus, the development of T cell epitope and B cell epitope based vaccines play an important role in future prospects for alternative treatment for allergy. The vaccine aims to induce the immune system so it will not react towards the allergen though the body al…

Cytotoxicity Test for Zn-Sr Cosubstituted Hydroxyapatite

The current report states the author’s experience as an intern at Badan Riset Inovasi dan Nasional (BRIN), under the department of Pusat Riset Material Maju (PRMM). The goal of this internship was to create a systematic review that discusses the cytotoxic effects of hydroxyapatite cosubstituted with zinc (Zn) and strontium (Sr) on osteoblastic cell lines, with the goal of possibly using this …

Cytotoxicity test for Hydroxyapatite-HPMC-Chitosan Injectable Bone Graft: A S…

This systematic review both serves as the author’s experience as an intern at Badan Riset dan Inovasi Nasional (BRIN), in the department of Pusat Riset Materi Maju (PRMM), under the guidance of Dr. Nendar Herdianto, M. Si, while being a substitute for a normal internship report. The goal of this internship was to create a systematic review that compiles the previous researches and discusses t…

In Vitro Cytotoxic Study of Marchantia paleacea Ethanolic Extract against Hum…

Bryophytes are known for its medicinal properties. Amongst them, liverwort (Marchantia paleacea) is one of the plants that confers pharmacological activity. This present study aimed to determine the potential cytotoxic activity M. paleacea ethanolic extract against human cervical adenocarcinoma (HeLa) and human epidermal keratinocytes (HaCaT) cell lines by means of MTT assay and cell count…

IN VITRO STUDY OF MARCHANTIA PALEACEA POTENTIAL AS CYTOPROTECTIVE AGENTS ON H…

In this study, the potential of Marchantia paleacea, a bryophyte that grows in the Cibodas Botanical Garden, was studied for its cytoprotective capability against oxidative stress. H was used. Although bryophytes have been used in traditional medicine for centuries, this group of plants is still poorly studied. Bryophytes have been shown to contain metabolites such as flavonoids, polypheno…

Characterization and Cytotoxicity Evaluation of Crude Ethanol Extract of the …

Gynura divaricata has been widely used as traditional Chinese medicine for treating a variety of diseases. The bioactive compounds of G. divaricata, especially its rich flavonoid and phenolic acid contents make the plant has potential to be used as an antimalarial. In order for a substance to be used as an antimalarial, it needs to have low toxicity against human cell…

In Vitro Anticancer Activity Evaluation of Daun Gatal (Laportea Decumana) Met…

Among the many causes of death, cancer has ranked second as the major contributor of mortality worldwide and has caused a high rate of mortality in Indonesia alone. Chemotherapy is a common treatment used to treat cancer, yet chemotherapy is cytotoxic to both cancer cells and healthy cells, causing a lot of undesired adverse effects such as hair loss, nausea, and anemia. Recently, plant-derived…

In-vitro Cytotoxic Activity Evaluation and Genomic DNA Fragmentation Detectio…

Despite being the second leading cause of death, treating cancer is still remarkably challenging. The most commonly used option to treat cancer is chemotherapy regardless of its toxicity not only to cancer cells but also to highly proliferative cells under normal physiological conditions such as hair follicle, bone marrow, and GI tract mucosa, which possibly decrease the patient's quality of li…

Cytotoxicity and Antioxidant Evaluation of Intsia Bijuga Extract

Edition

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ISBN/ISSN

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Collation

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Series Title

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Call Number

Intrep202103003 FEB c