Pseudomonas aeruginosa is a significant opportunistic pathogen causing healthcare-associated infections (HAI)worldwide, its ability to form biofilms contributes to antibiotic resistance, resulting in the increased difficulty for treatment, thus finding a new therapeutic approach is crucial.
Capsicum annuum, or chili pepper, is known from traditional medicine to have anti-tumor properties. Recent researches isolated to compound responsible to be Capsaicin, with few researches opposing this notion. Since there are some disagreements as to the validity of this claim, it is important that further tests need to be conducted to prove or disprove the point. Hence, this thesis aimed to…
Candida albicans is a yeast that resides on the human skin, however it can become an opportunistic pathogen when the immune system is compromised or there are imbalances in the microenvironment. This microorganism can cause candidiasis which is able to cause high mortality rates in especially immunocompromised patients. Treating this infection is highly difficult due to similarities in stru…
Hepatocellular carcinoma (HCC) poses a significant challenge in clinical management due to late-stage diagnosis and limited curative interventions. The imperative to develop more efficacious therapeutic approaches for HCC underscores the exploration of oncolytic virotherapy, an innovative treatment modality exhibiting promising antitumor properties. Among potential oncolytic vectors, the measle…
Psoriasis is an autoimmune skin disorder that has impacted the global population from children to adults. Psoriasis is characterized by unusual proliferation of keratinocytes, leading to itchy, bleeding, scaly, and red lesions due to increased immune system activity. Existing topical treatments often result in side effects, emphasizing the necessity for advanced drug discovery in managing psori…
The current report states the author’s experience as an intern at Badan Riset Inovasi dan Nasional (BRIN), under the department of Pusat Riset Material Maju (PRMM). The goal of this internship was to create a systematic review that discusses the cytotoxic effects of hydroxyapatite cosubstituted with zinc (Zn) and strontium (Sr) on osteoblastic cell lines, with the goal of possibly using this …
This systematic review both serves as the author’s experience as an intern at Badan Riset dan Inovasi Nasional (BRIN), in the department of Pusat Riset Materi Maju (PRMM), under the guidance of Dr. Nendar Herdianto, M. Si, while being a substitute for a normal internship report. The goal of this internship was to create a systematic review that compiles the previous researches and discusses t…
Despite being the second leading cause of death, treating cancer is still remarkably challenging. The most commonly used option to treat cancer is chemotherapy regardless of its toxicity not only to cancer cells but also to highly proliferative cells under normal physiological conditions such as hair follicle, bone marrow, and GI tract mucosa, which possibly decrease the patient's quality of li…