This subchronic toxicity study assessed the delayed toxicity and reversibility of fennel extract in male and female mice. To ascertain any delayed toxicity and potential for recovery, a separate satellite group received oral doses of fennel extract at a dose of 1000 mg/kg/day of body weight for a duration of 90 days, followed by 28-days with no treatment. There were no abnormalities observed in…
F. vulgare is a perennial herb that has been traditionally used as medicine for a variety of ailments. It has also been used as a medication due to its antimicrobial, antifungal, and antiviral properties. Previous studies have highlighted issues associated with the poor quality of therapeutic herbal products commercially available, thus a standardization for safety and toxicity profiling of her…
The CoronaVirus Disease 2019 (COVID-19) caused by SARS-CoV-2 continues to be a global pandemic with substantial socioeconomic damages. Exploration of bioactive compounds from herbal resources with potential anti SARS-CoV-2 effects are currently on the rise. In particular, naturally-derived flavonoids are reported for its capability to inhibit 3-chymotrypsin like-protease (3CL ), a promising…
Since coronavirus disease 19 (COVID-19) was first found in China on 12 December 2019, finding potential treatments for this virus have always been pushed by many countries. The polyphenolic compound contained in Foeniculum vulgare seeds extract has been found to have antioxidant activity and is linked to the protection of diseases. Thus, the aim of this project is to perform extraction of Foeni…