This subchronic toxicity study assessed the delayed toxicity and reversibility of fennel extract in male and female mice. To ascertain any delayed toxicity and potential for recovery, a separate satellite group received oral doses of fennel extract at a dose of 1000 mg/kg/day of body weight for a duration of 90 days, followed by 28-days with no treatment. There were no abnormalities observed in…
Foeniculum vulgare or known as adas in Indonesia is a medicinal plant that belongs to the umbelliferae family. It has a lot of pharmacological properties such as antiviral, antimicrobial, antioxidant, anti-inflammatory, anti-anxiety, gastro-protective, estrogenic-like, cardiovascular, lipid-lowering, anti-mutagenic, anti-diabetic, anti-cancer activity, hepatoprotective, and memory-protective ch…
Herbal medicines are often used as therapeutic agents and contains one or multiple active compounds such as alkaloids, phenolics, and flavonoids. Flavonoids are natural compounds which are essential for pharmacological activity of plants and are known for antioxidant, antibacterial, and antiviral properties. As antiviral properties, Juglanin and quercetin are known to inhibit COVID-19 repli…
Since coronavirus disease 19 (COVID-19) was first found in China on 12 December 2019, finding potential treatments for this virus have always been pushed by many countries. The polyphenolic compound contained in Foeniculum vulgare seeds extract has been found to have antioxidant activity and is linked to the protection of diseases. Thus, the aim of this project is to perform extraction of Foeni…