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The Effect of Freeze-Drying Parameters on Secretome Anti-Aging Potency In Vit…
The idea of anti-aging has become increasingly significant worldwide as people have begun to understand how aging impacts human health significantly. Currently, various synthetic anti-aging agents are available in the market. However, synthetic agents are often associated with several adverse effects. Hence, people are now looking for other alternatives. One of the candidates is secretome from …
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- BM 23-018
The Effect of Primary Drying Temperature on Freeze-dried Mesenchymal Stem Cel…
Mesenchymal stem cells (MSC) are multipotent stromal cells capable of regenerating and differentiating into various tissues. MSCs can secrete over 200 different types of these bioactive molecules called secretomes, that contain chemokines, interleukins, growth factors, and extracellular matrix proteins. However, the bioactive molecules present in these can degrade over time due to temperatu…
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- BT 23-003
Influence of Osmotic Dehydration Pretreatment on the Physicochemical Characte…
Strawberries are known for their vibrant color, juicy texture, and enticing sweetness, which may change as they ripen. A freeze-drying (FD) process was used to alter the changes. However, because FD is a time-consuming process, a pretreatment process is essential for accelerating the FD process. This research aims to improve the FD process for strawberries by using osmotic dehydration (OD) a…
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- FT 23-013
Accelerated Shelf-Life Testing of Freeze-Dried Red Fruit Oil (Pandanus conoid…
Red fruit (Pandanus conoideus Lam.) is a native fruit from Papua, Indonesia, usually processed into oil due to its high lipid content. Multiple studies have encapsulated red fruit oil and observed its stability, but the shelf-life estimation of freeze-dried is yet to be determined. Accelerated shelf-life testing (ASLT) is utilized in this study with the Arrhenius modelling to observe the deg…
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- FT 23-005
The Effect of Freezing Time Variation as Critical Process Parameters In Freez…
Mesenchymal stem cells secretome (MSC-S) are non-hematopoietic multipotent stromal cells that have the ability to renew themselves and differentiate into multilineages, which has been shown to have therapeutic effects on wound healing process. In order to produce a “ready-off-the-shelf ” secretome powder, a lyophilization or also known as freeze-drying process needs to be carried out. I…
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- PHA 23-009
The Effect of Freezing Time Variation In Freeze-Drying on Mesenchymal Stem Ce…
Secretome is a bioactive substance secreted by MSCs in a conditioned media, which consists of growth factors, other substances that are able to provide a biological response by undergoing signal transduction. A secretome-based therapy has gained attention as a novel cosmetic active ingredient for its antioxidant and wound healing properties. To overcome the stability issue, freeze-drying te…
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- PHA 23-003
The Effect of Freezing Time Variation in Freeze-Drying on Protein Characteris…
esenchymal stem cells (MSCs) have been long studied and developed as a regenerative medicine supported by their secreted bioactive molecules called secretome or MSC-secretome (MSC-S) that contain soluble factors and extracellular vesicles (EVs). Unlike the MSC-based therapy that utilized the whole cells, secretome is a cell-free therapy that would ease the future treatment development as it …
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- PHA 23-010
CHARACTERIZATION AND COMPARISON OF THE FREEZE-DRYING PROCESS AT PT. HIJAUKAN …
"Freeze-drying, also known as lyophilization, is a drying method that is superior to other drying methods in that it retains aroma, flavor, aroma, and nutrition better while also extending the overall shelf-life of fruits and vegetables. Freeze-drying follows 3 stages/phases, freezing, primary drying, and secondary drying. Different machines have different freeze-drying settings where PT. H…
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- EP FT001
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