Cervical cancer (CC) is one of the most prevalent malignancies in females worldwide, in which one of its major causative agents is human papillomavirus type 16 (HPV16). The current HPV screening measures are responsible for reducing CC incidence; however, some limitations still persist which brings about the necessity to investigate novel biomarkers. The HPV16 genome contains several genes with…
Laportea decumana often known as itchy leaf, is a Papuan wild plant. Its antiviral activity was investigated for future recommendations of possibly new medication development, and the NDV virus was employed as a safe model for infection. To investigate the toxicity of itching leaves, a cytotoxicity experiment employing MTS was performed. Plaque assays were performed to evaluate the antiviral ac…
Atopic dermatitis is a chronic skin disease that affects 20% of children aged three to six months and 3% of adults worldwide. Despite its prevalence, the exact cause of the disease remains unclear due to its complexity of the disease. Many available drugs in the market for treating AD focus on preventing the disease from worsening, such as managing skin infection, hydration, inflammation, a…
Pneumonia is an infectious lung disease that is commonly found in secondary bacterial co-infection in severe COVID-19 infection, namely COVID Pneumonia, and it is accounted for higher morbidity and mortality rate than COVID-19 infection alone. To find immunomodulators that able to act as gene expression regulators is important to minimise the occurrence of cytokine storms. Three kinds of In…
A healthy and moisturized skin is the result of a healthy and functioning barrier function. The barrier function mainly consists of the CE layer of the epidermis, which is formed by the cross-linking of FLG, IVL, and LOR genes that are catalyzed by TGM-1 gene. However, due to many factors, the moisture and water content in the skin may be altered; thus, resulting in dry skin. The usage of moist…