Analyzing the DNA Stability of U87 Glioblastoma Cells After Co-Culturing With…

Edition

-

ISBN/ISSN

EP061

Collation

58 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP BT-009

Preliminary investigation of glutamine transporter SLC7A8 role in mediating c…

Glioblastoma multiforme (GBM) is a highly aggressive glioma that is reported to exhibit elevated glutamine uptake and metabolism, termed as glutamine addiction, often associated with poor patient prognosis. Recently, a preliminary study identified glutamine transporter SLC7A8 to be highly upregulated in resistant GBM and associated with poor prognosis, with results intriguingly showing dist…

Investigating the Role of Tumor-Associated Neutrophils (TANs) in the Suppress…

Glioblastoma (GBM) is known as a highly aggressive and malignant form of brain cancer. Despite advances in understanding the genetic and molecular basis of glioblastoma, it has a poor prognosis with a median survival rate of 9 months. The complex interplay between malignant cells and the surrounding tumor microenvironment (TME) plays a pivotal role in tumor progression and treatment respons…

Single-cell Analysis of Long Non-coding RNAs (lncRNAs) in Tumor-Associated Ma…

Glioblastoma (GBM) is the most severe type of brain tumor with poor prognosis and low survival rate, characterized by molecular heterogeneity and immunosuppressive microenvironment which pose a significant challenge in improving treatment strategies. It is found that the abundance of tumor- associated macrophages (TAMs) in the GBM microenvironment contributes significantly to tumor progre…

Evaluating the Role of Gene X in Glioblastoma Tumorigenesis and Temozolomide …

Temozolomide (TMZ) stands as the primary chemotherapy choice for glioblastoma multiforme (GBM), yet resistance frequently emerges in patients, leading to tumor recurrence and worsened prognoses. A recent study reported upregulation of glutamine and glutamate transport and metabolism in TMZresistant GBM in silico, particularly highlighting the upregulation of Gene X. Given the reported glutamine…

Characterization Of Pediococcus Acidilactici Postbiotics Loaded Bacterial Cel…

Glioblastoma is the most prevalent type of malignant brain tumor, with a fatality rate close to 100%. The failure of glioblastoma treatment is mainly attributed to the high proliferation and invasion rate of glioblastoma cells, in addition to the presence of glioblastoma stem cells, all of which are regulated by the Notch signaling pathway. Past studies have observed that the Notch signaling…

Investigating The Role Of Notch Signaling And Its Regulator In The Progressio…

Glioblastoma is the most prevalent type of malignant brain tumor, with a fatality rate close to 100%. The failure of glioblastoma treatment is mainly attributed to the high proliferation and invasion rate of glioblastoma cells, in addition to the presence of glioblastoma stem cells, all of which are regulated by the Notch signaling pathway. Past studies have observed that the Notch signaling…