Pediococcus acidilactici is a gram-positive lactic acid bacteria (LAB) widely used as a probiotic due to its safety, benefits, and ability to survive in the harsh environment of the gastrointestinal (GI) tract. One of the challenges for probiotic species is the presence of bile salt, which can degrade bacterial cell membrane due to its main function in lipid solubilization. Bile salt can als…