Cancer is a complex disease that involves the growth of cells inside the body. In 2020, more than 10 million people died from cancer worldwide. One of them is brain cancer. Brain cancer itself has higher mortality rate on men rather than women. One of the tools that play pivotal role in detecting cancer is Artificial Intelligence. The Artificial Intelligence helps on analyzing the image pat…
In order to address the needs of infants with cow's milk allergy, two formulations of a semi-solid, dairy-free, ready-to-use complementary food were developed. These formulations were created in an attempt to fulfill BPOM regulations and infant recommended dietary allowance values, differing only in their peanut oil to palm rations: formula 1 (30:177) and formula 2 (50:157). Both Formulae were …
Lipid-based dairy free RUCF is a ready to use complementary food made with local ingredients. The important quality of the RUCF is the nutrient composition and physicochemical properties, especially the oil separation and PV. With the problems encountered with oil separation in previous study about development of lipid-based dairy free RUCF, this study will reformulate the RUCF with adjuste…
Capsicum annuum, or chili pepper, is known from traditional medicine to have anti-tumor properties. Recent researches isolated to compound responsible to be Capsaicin, with few researches opposing this notion. Since there are some disagreements as to the validity of this claim, it is important that further tests need to be conducted to prove or disprove the point. Hence, this thesis aimed to…
DNA damage is a complex phenomenon arising from both endogenous and exogenous sources, posing threats to genomic stability and necessitating an effective DNA damage response (DDR). A dysfunctional DDR can cause genomic instability, which is defined by a higher frequency of DNA mutations. Genomic instability is a common feature of many cancers, and it can result in oncogenic mutations and tu…
Paediatric cancer accounts for the majority of cancer-related mortality in children. Although current treatment increased the overall survival rates, young individuals often encounter life-long side effects from toxic therapies. Therefore, there is an urgent need for targeted therapies aimed at tumour-specific vulnerabilities for greater specificity and reduced toxicity, in which precision m…
This study focuses on the characterization of bacterial communities in Takakura compost specifically applied to Saga plants. Takakura compost, known for its simplicity, cost-effectiveness, and efficacy in producing high-quality compost, utilizes the natural processes of microorganisms to break down organic materials. The research involves the analysis of bacterial communities during the comp…
Pasta is one of the most popular staple foods for many consumers. Colored pasta has emerged as a creative approach to improve product appearance. Red Fruit Oil (RFO) (Pandanus conoideus Lam) can serve as natural colorants with potential health benefits. Encapsulation method using spray drying was applied to RFO to lower the susceptibility and mask unpleasant sensory profiles. This project a…
Stunting remains a significant malnutrition issue globally, with a prevalence of 14.4% in East Jakarta at the end of 2023. Despite this, studies focusing on stunting among children aged 6-59 months in Jakarta were still lacking. The high incidence of stunting is linked to several factors, including parental socio-demographic status, breastfeeding practices, dairy product intake, child healt…
Cognition is an individual’s ability to learn, solve, and appropriately use stored information. Cognitive deficits can manifest in various ways and are commonly caused mainly by age, and other health conditions such as neurodegenerative diseases as well as side effects from certain drugs. Currently, natural supplements using herbal plants have been investigated as cognitive enhancers and b…
Originating from the seeds of Sterculia lychnophora Hance, Pangdahai has traditionally been used as a tea for various ailments and is now part of modern dietary practices. Recent studies have revealed the pharmacological activities of Pangdahai extracts, yet the specific compounds responsible for these effects remain unidentified. This study aimed to bridge that gap using a multi-step approa…
"Flavivirus is a genus of positive-sense single-stranded RNA viruses that are mostly transmitted through mosquito or tick vectors and are known to be emerging and re-emerging viruses. Some of the significant species that have been reported to cause an outbreak globally include DENV, YFV, WNV, ZIKV and JEV. While some vaccines have been successful in preventing infections caused by certain f…
Malaria is an infectious illness caused by Plasmodium parasites and vectored by Anopheles mosquitoes. Recent developments in genetic engineering have opened the doors to paratransgenesis as a technique to combat malaria. This preliminary in silico project aims to investigate an unorthodox paratransgenic approach to eliminating Plasmodium cells in the mosquito. A recombinant Ti plasmid, inte…
Green supply chain management has been a popular approach for many businesses to respond to many environmental issues, such as climate change, loss of biodiversity, resource depletion, greenhouse emissions, and climate change. This research aims to explore the effects of supply chain management on organizational sustainability performance and how it affects the products produced by the manu…
The widespread trend of global industrialization in Indonesia has resulted in the depletion of natural resources and environmental destruction. Indonesia has been undergoing recent changes in accordance with the 2030 agenda to potentially achieve the Sustainable Development Goals and reduce carbon footprint. The pivotal role of an organization’s Human Resource (HR) Department in cultivatin…
Artificial Intelligence (AI) has become a popular and significant technology that has strongly impacted multiple industries through various services such as automation. However, the AI’s success depends on its strong and effective implementation of AI systems, requiring managers to have positive perceptions and acceptance towards implementing and operating AI, and this can help the Indone…
The actual disparities of alcohol consumption and preference between men and women varies among countries, cultures, and individuals. The late years of adolescence to early adulthood can be a challenging yet explorative period for many young adults. Generally, this period becomes associated with an increased interest and consumption towards alcoholic beverages, which allows people to develop th…
This study explores the impact of stabilizers (guar gum, gellan gum, locust bean gum, carrageenan) on the appearance,viscosity, and sensory evaluation of recombinant chocolate milk. Through viscosity measurements and sensory evaluations, it aims to understand how stabilizers influence sensory and physical characteristics for product development. In the quest for superior dairy products, man…
Infantile spasm is a type of epilepsy that occurs in infants that is characterized by the sudden movement throughout the whole body. It is crucial to detect the disease and undergo suitable treatments as soon as possible in order to minimize the potential negative long-term effect in learning development. One of the most effective treatments is the usage of anti-epileptic drug Vigabatrin that i…
Currently, the demand for sustainable platforms to address environmental problem is arising. Biodiesel is an eco-friendly alternative for regular diesel as it has many advantages, and the most important thing is derived from environmental-friendly source, such as microalgae. Several microalgae are known for being able to synthesize lipids and even higher concentration. Newly microalgal strains …
Sweet soy sauce is a popular condiment in Indonesia, and it is mostly available in liquid form. Converting the product into powder form could provide several benefits, such as lower distribution cost and utilization in more types of product. In this study, sweet soy sauce was spray-dried in three different formulations (sweet soy sauce solids:maltodextrin ratio of 2:1, 1:1, and 1:2) and t…
Noodles are a staple food in Asia. However, since it is made using wheat flour which is high in carbohydrate, protein enrichment by adding other ingredients like cricket powder and nutritional yeast can be done. This study aimed to increase the protein content in noodles by incorporating cricket powder and nutritional yeast with different substitution levels (10, 15, and 20%) towards the …
This study aimed to develop a lipid-based paste form of Ready-to-Use Complementary Food (RUCF) using locally available ingredients, while investigating the physicochemical changes during 21 days of storage. Three formulations were proposed and assessed using B one touch viscometer for viscosity, CS410 handheld colorimeter for color, pawkit water activity analyzer for water activity, and e…
The current report describes the experience that the author gained during her 11 months of internship placement at Indonesia International Institute for Life Sciences (i3L). The internship was organized by Ms. Elizabeth Sidhartha, B.Sc., M.Sc. (a Biomedicine faculty) and was conducted online. The goal of this internship is to produce a systematic review discussing the potential of Plasmodium fa…
The global food industry grapples with significant waste and loss, with more than one-third of total food production. This waste, extending from agricultural production to consumption, poses environmental and disposal challenges. Postharvest losses, particularly in fruits, contribute significantly, with over 60% of cultivated land crops going to waste. Addressing this issue is crucial for econo…
Human immunodeficiency virus 1 (HIV-1) has persistently been a global health concern, infecting 39 million people around the world with 1.3 million cases increment in 2020, leading to severe immunodeficiency (UNAIDS, 2023). While mammalian genomes show evidence of repeated infection with retroviral pathogens, this co-evolution has resulted in the emergence of defense mechanisms that pre…
"The study delves into the characterization of bacterial communities within Takakura composting. Takakura composting is a method integral to organic waste management, and serves as the focal point for understanding microbial dynamics during decomposition. The research aims to make takakura compost with two different compositions and characterize the bacterial community in the Takakura compo…
Tuak is an alcoholic beverage from Southeast Asian countries, such as Indonesia and Malaysia, prepared by fermenting starchy materials (e.g., rice, palm sap, coconut sap or water). Tuak production factors and recipes vary from one maker to another, including the type of substrate used, sugar level, water level, fermentation time, and even the starter culture used. These factors affect the micro…
This research project addresses the challenge of food waste at Hangry Indonesia, a cloud kitchen restaurant. Focusing on rice, a staple in their menu, the study aims to create a sustainable system to reduce food waste when sales fall short of targets. Additionally, the project explores the impact of reheating frozen rice on texture, specifically addressing issues such as browning and hard…
This study was completed by the author who had the opportunity to do an internship as an E-commerce marketing intern at Kalbe Nutritionals. Kalbe Nutritionals assure the products bring goodness to life for all of the customers, both in Indonesia and across the world, and are convinced that the company should constantly provide the most excellent nutrition solution to each individual. Nowadays, …
Genome Wide Association Studies (GWAS) aims to find genomic variants that correlates with the occurrence of certain traits within a population. Various tools and algorithms can be utilized to conduct GWAS, among them are PLINK, Hail, and VariantSpark. In this study, a GWAS analysis pipeline was developed using PLINK, Hail, and VariantSpark to assess their performance in conduction GWAS asso…
Food quality is an important aspect to be upheld especially for big companies whose end consumers are babies, such as Danone. Danone or every other company has their own standard of product quality which has to be constantly maintained by everyone in the value chain, including suppliers. However, suppliers’ performances—which consequently affect the company as well—are not always satisfac…
Folic acid is an important vitamin for fetal development and nucleotide and amino acid metabolism. Corn is one of the good sources for folic acid while tempeh fermentation has been reported to increase folic acid content. To concentrate further, membrane filtration is a promising technology. This study aims to understand the effect of microfiltration conditions towards the increase of folic aci…
Acne, also known as acne vulgaris, is a chronic inflammatory illness that affects the sebaceous glands and is characterized by the production of erythematous nodules, pustules, and papules, which can scar. Acne is the eighth most prevalent disease, estimated to affect 9.4 % of the global population. Specifically in Indonesia, the prevalence of acne is increasing year by year. Acne has affected …