Induction of Apoptosis in TKI-Resistant Non-Small Cell Lung Cancer: Evaluatin…

Edition

-

ISBN/ISSN

EP070

Collation

32 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP BT-018

Investigation of Ethyl-methanesulfonate (EMS) Treatment as A Mutagenesis Appr…

As the human population grows, the demand for organoleptic properties in food has linearly increased, including the use of harmful synthetic colorant. Therefore, carotenoids, as a secondary metabolites and natural compounds, can be used as an alternative to natural food preservatives. They are also attributed to antioxidant properties which are beneficial for human consumption and health. T…

Lineage Tree: Visualization Platform for Exploring SARS-CoV-2 Pango Lineage N…

Public health surveillance plays a pivotal role in ending the COVID-19 emergency, especially monitoring the emergence of new lineages. A dynamic SARS-CoV-2 lineage naming system, known as the Pango nomenclature system currently being used to assist genomic epidemiology. Currently, researchers manually draw charts to visualize mutations found in major pango lineages that shape the evolutionar…

Optimization of PCR-Based Mutation Detection Kit for Detecting L858R Mutation…

Non-small-cell lung cancer (NSCLC) comprises the majority of lung cancer about 75-80%, and a quarter of NSCLC cases have mutations in the epidermal growth factor receptor (EGFR) gene. Adenocarcinomas of the lung harboring the L858R mutation in exon 21 have proven to be more adverse in terms of prognosis than exon 19 mutations. Therefore, developing highly sensitive and selective methods to …

Web-based visualization tools for frameshift detection in SARS-CoV 2 sequenci…

This internship report titled “WEB-BASED VISUALIZATION TOOLS FOR FRAMESHIFT DETECTION IN SARS-COV 2 SEQUENCING AT GENOMICS HUB COMPANY (GSI LAB)” covers the author ’s internship experiences and tasks to develop a web-based tool. Based on the natural behavior of viruses and/or diseases that always mutate, it is possible for the coronavirus to mutate and produce new variant types which …

Detection of Mutation in Exons of HBB, HBA1, and HBA2 Genes of Thalassemia Pa…

Thalassemia can be defined as a recessive autosomal blood disorder that mainly affects the amount and normal function of hemoglobin that works primarily to carry oxygen throughout the body. The low amount or absence of hemoglobin within the red blood cells can cause a tremendous effect on the body as the RBCs could be degraded, creating an anemic condition for those who suffer from the dis…

Investigation of XRCC4/C-terminus Phosphorylation Role on Xkr4 Activation

Xk-related protein 4 (Xkr4) protein is one of the scramblases that can expose phosphatidylserine (PS) as an “eat-me” signal in apoptotic cells. Xkr4 is activated in two steps: Dimer formation after caspase-mediated cleavage of its cytoplasmic region, followed by direct binding of the C-terminal fragment of X-Ray Repair Cross Complementing 4 (XRCC4/C-terminus) to the Xkr4 dimer. It has b…