Centella asiatica also referred to as Gotu Kola is a plant that has been utilized for hundreds of years in both traditional and modern medicine. In skin care products, it has been claimed that Centella asiatica leaf extract stimulates collagen production, reorganizes the damaged tissue, restores tissue firmness and skin elasticity, and improves the appearance of the skin. Triterpenoid compounds…
Skin aging is an inevitable process in which the skin declines in quality which can be affected by intrinsic and extrinsic factors. One of the important factors contributing to skin aging is the accumulation of ROS (Reactive Oxygen Species). The ROS model was often used to study the effect of compounds that could affect skin aging and the most commonly used ROS model is H2O2, has been associate…
Skin anti-aging is a primary focus in derma cosmetics, targeting the reactive oxidative species (ROS) pathway for developing anti-aging therapies due to its role in the degradation of dermal extracellular matrix (EDM). Collagen type 1 is targeted to combat skin aging due to its role in preventing wrinkles formation and re-epithelization of human keratinocytes (HaCaT). Cell-free treatments have …
Modified cassava flour (mocaf), is one of the cassava fermentation products using lactic acid bacteria. Mocaf is generally safe for people that have certain conditions due to its gluten-free. It also contains low-protein but rich in carbohydrates. Fermentation starter can affect the quality of mocaf. Pediococcus acidilactici has a potential as a starter for fermented food. Until now there is no…
Adolescent nutrition and health can improve by practicing healthy eating habits, engaging in regular physical activity, and maintaining good personal hygiene. A healthy breakfast and balanced diet can help teens focus better in class, build strong bones and muscles via regular exercise, and improve their self-worth and physical cleanliness through good personal hygiene. Teenagers in Indonesia a…
Food quality is an important aspect to be upheld especially for big companies whose end consumers are babies, such as Danone. Danone or every other company has their own standard of product quality which has to be constantly maintained by everyone in the value chain, including suppliers. However, suppliers’ performances—which consequently affect the company as well—are not always satisfac…
Cognitive impairments in thinking are the example of neurodegenerative diseases that happened in Alzheimer Disease (AD). Short memory loss (dementia) is one of the symptoms, showed by 60-70% cases found and gradually progress in declination of thinking. Therefore, dementia usually is associated in AD. Lately, an inhibitory neurotransmitter called GABA is known for its relation with working memo…
Cardiovascular diseases are one of the most prevalent non-communicating diseases, and also one of the leading causes of death globally. In Indonesia alone, cardiovascular diseases are one of the leading causes of death. However, many people are still unaware about the early prevention and mitigation of cardiovascular disease, increasing the prevalence of the diseases. The innovation of self-dia…
Nile Tilapia (Oreochromis niloticus) is a notable species reared in the aquaculture industry. It is famous for its protein content, rapid growth rate and adaptability in various types of water. It makes Tilapia advantageous in aquaculture for mass production through intensification. However, the stack volume of rearing may lead to disease manifestation by bacteria, fungi, parasites, and viruses…
Cocoa is widely used as a raw ingredient in both confectionery and non-confectionery products in the food industry. In the food industry, the most commonly used cocoa derivatives product is cocoa powder. In this project, cocoa powder would be used as one of the ingredients inside the chocolate cream filling. There would be one control sample and three prototypes of cream filling with the reduct…
PT Takasago International Indonesia is a company that produced flavors and fragrances. Takasago has two sites, which are headquarter and production site in Indonesia. Headquarter site is responsible for handling and managing the customer request, meanwhile production site is responsible for producing flavor and fragrances product. One of division in the headquarter site is sweet application div…
Folic acid is an important vitamin for fetal development and nucleotide and amino acid metabolism. Corn is one of the good sources for folic acid while tempeh fermentation has been reported to increase folic acid content. To concentrate further, membrane filtration is a promising technology. This study aims to understand the effect of microfiltration conditions towards the increase of folic aci…
Diabetes mellitus is a global health issue that is gaining traction in our healthcare system which leads to impaired wound healing and results in chronic ulcers, these increases the risk of amputation and disease mortality rate by 50-59% in 2020. Therefore, better inventions to treat diabetic ulcers are required. A bio-cellulose hydrogel is a form of wound dressing that can aid in protecting t…
Soy is a widely popular seasoning in East and Southeast Asian Cuisine, traditionally made by cooking soybeans and inoculating them with Aspergilius sojae yeast for five-day fermentation period, followed by brining. This project aimed to explore the potential of pigeon pea (Cajanus cajan) as a subtitute for soybean in the production of sweet soy sauce. Both soybean and pigeon pea sweet soy sauc…
In the attempt of reducing fruit waste from fruit industry, thawed fruit and lemon waste (peel and pith) can be utilized to produce jam. Pectin, a vital gelling agent in jam making is abundant in lemon waste, however, its yield and effectiveness depends on the extraction method. In this study, the lemon pectin was extracted from using heat and strained with cheesecloth. The pectin was then adde…
Packaging plays an important role in maintaining product quality. Some of packaging's basic functions are containment, protection, communication, and convenience. As a communication function, it not only provides basic information about the product, but also as a commercial purpose to attract customers. However, some cases might happen in the development of visual defects of packaging which red…
Back slopping is referred to as the small inoculation of a previous successful fermentation product to the raw material, as the starter culture. One example of the traditional fermented product that utilizes the back-slopping methods is dadih. As it is an artisanal product that is made using traditional methods that involve humans and is prone to contamination, such as Staphylococcus aureus…
In recent years, a number small and medium-sized businesses selling eco-friendly and sustainable products in Indonesia have started as the result of increasing demand from generations Y and Z. Known for their “digital savvy” attitude and synonymous with social media usage, many of these businesses use social media sites,such asInstagram, to initiate “green marketing” activities promotin…
The market of slimming tea has grown significantly in recent years as a result of rising demand for natural and organic products on growing awareness of the importance and maintaining a healthy lifestyle. This broad industry offers a range of slimming tea products, from conventional blends to specialty formulas created to meet particular health objectives. Consumer opinions on slimming tea vary…
In recent years, beauty companies have become one of the most succesful business in the world. The cosmetic products are already being produced with advanced technology that can create various new cosmetics products each year. However, the ingredients inside cosmetic formulations become main concerns to many consumers for health concerns, which make natural products in high demand. This study w…
Acne, also known as acne vulgaris, is a chronic inflammatory illness that affects the sebaceous glands and is characterized by the production of erythematous nodules, pustules, and papules, which can scar. Acne is the eighth most prevalent disease, estimated to affect 9.4 % of the global population. Specifically in Indonesia, the prevalence of acne is increasing year by year. Acne has affected …
Incorporating bioactive substances into seasoning powder may be done to provide additional benefits. Young rice (Oryza sativa L.) leaves are known for their secondary metabolites, however, they are unstable to external factors. The objectives of this study are to evaluate the total phenolic content (TPC) of raw and encapsulated rice leaf extract powder, and evaluate the addition of raw and non-…
In the past decades, the allergic disease prevalence has been increasing worldwide. It is estimated that 5-30% of populations in all America, Southeast Asia (such as Indonesia, Malaysia, Thailand, Singapore, etc), Europe, and Australia have sensitivity and/or skin reactivity towards dust mites. House dust mites (HDM) are able to cause severe allergic reactions as well as represent the biggest s…
Accurate automated and reliable P-wave detection is important for electrocardiography (ECG) analysis to help doctors treat heart diseases in patients. Unlike QRS detection, P-waves detection has not been studied as much as QRS-Complex detection. This work introduced methods to detect and locate P-waves in normal and pathological conditions. Pathologies included werePVC, NOD, Afib, Aflutter, and…
The prevalence of stunting continues to be a severe public health concern that has hampered the nation's expansion and progress. One of the factors causing the high incidence of stunting was ignorance about the causes of stunting in the first 1000 days of life. Pregnant women have a crucial role in addressing the nutritional intake of themselves and the children so stunting could be prevented e…
Technology development has rapidly increased in every division, especially in healthcare. Hospital management started to improve by incorporating technological tools and systems in this era. With the system prepared from the hospital, patient data can be saved and prepared systematically to be used as a queue line of appointments. It could be improved by using a chatbot which increases the effi…
Extrusion cooking is one of the preferred methods for food processing because it is a continuous process, with high productivity, high temperature, and short cooking period that removes both harmful microorganisms and anti-nutrient enzymes to produce products with significant retention of nutrients and a longer shelf-life. In this research monoglycerides as the emulsifier was used to produce wh…
Increasing population growth globally has a greater impact on waste production. Food waste at the household level is the largest point of concern which is strongly influenced by consumers' behaviors. The issue of waste and its impact has already been a concern in Indonesia through the Regulation Government that produced to support reducing waste in general with the 3R (Reduce,Reuse, Recycle) im…
Early recognition and detection of cardiovascular disease is crucial in saving the patient’s life. One of these early symptoms are arrhythmia, a condition where there is an unusual rhythm or rate in the heartbeat, and one of the common types of arrhythmia is premature atrial contraction (PAC). PAC is considered benign and does not possess any harm to the patients. However, PAC could be a prec…
In 2019, approximately 17.9 million people died because of cardiovascular disease (CVD). In the clinical immersion conducted at Lira Medika, Heart Failure (HF) is a dangerous disease that needs proper health monitoring. The common technology used to monitor heart disease is the electrocardiogram (ECG). But the concerns of electrocardiogram (ECG) raw data are hardly examined by medical experts d…
Plant-based milk alternatives have been given increasing importance by consumers in recent years due to their concerns towards the health, environment, and dietary lifestyle of cow’s milk. No prior study has explored the factors influencing the consumer behavior towards plant-based milk alternatives (PBMAs) within a unified framework. Therefore, this study attempts to predict the factor affec…
The most important sources of biomolecules that can be screened from plant components are thought to be plant extracts. These biomolecules may be extracted from medicinal plants using a variety of solvents and extraction techniques. Due to their simplicity, effectiveness, and broad application, solvent extractions are the most widely used processes to create extracts from plant materials. Binah…
Snacks are often correlated with bad nutritional content due to high calories, fat, and carbohydrates with low essential protein, vitamins, and minerals. Moringa Oleifera and Lacryma Coix -Jobi L. could be the main ingredient for snacks due to their high fiber content, high antioxidant value, and low glycemic index. Both of the ingredients are easily cultivated and commonly found. However, …
The options for commercially available ready-to-use complementary foods (RUCF) is currently limited to dried products which are not suitable for younger infants. In addition, 2 – 7.5% of Indonesian infants are estimated to have cow milk protein allergy (CMPA) and are at risk of deficiencies in protein, fat, and micronutrients by avoiding the highly-prevalent dairy powder. This study aims to d…
The skin is a vital outer layer that serves as protection. Once the protective layer is disrupted, for example the formation of wounds due to outer layer damage, it may increase the likelihood of contraction skin infection, which is a global burden. When open wounds are in contact with microorganisms, it allows attachment and proliferation, resulting in the development of biofilms. Antibiotics …
Cervical cancer is the fourth most prevalent cancer and is the primary cause of mortality among women on a global scale. It is deadly once metastasize and therefore its early detection and prevention of its metastasis was crucial for the survival of the patient. Treatment targeting the prevention of metastasis was a necessity. Laportea decumana is a plant which has been shown to possess anti-ca…
Diabetes, which is categorized into type 1 and type 2, is caused by deficiency in blood glucose regulation, which causes organ damage. While type 2 diabetes includes insulin resistance, type 1 diabetes results from inadequate insulin production. Even among teenagers, the prevalence of type 2 diabetes is growing globally and is mostly related to lifestyle factors. Anti-diabetic drugs attempt to …
The current report states the author’s experience as an intern at Badan Riset Inovasi dan Nasional (BRIN), under the department of Pusat Riset Material Maju (PRMM). The goal of this internship was to create a systematic review that discusses the cytotoxic effects of hydroxyapatite cosubstituted with zinc (Zn) and strontium (Sr) on osteoblastic cell lines, with the goal of possibly using this …
Multiple myeloma (MM) presents as a significant public health challenge in Indonesia due to their high incidence and mortality rates. Due to its heterogeneous genetic landscape which plays a crucial role in determining patient prognosis, personalised treatment strategies need to be employed. This highlights the importance of the identification of genetic aberrancies in multiple myeloma patients…
This study explores the research that was carried out in Jakarta, Indonesia at the Indonesia International Institute for Life Sciences (i3L). The problem of drug-resistant forms of the malariacausing parasite Plasmodium falciparum in Indonesia is the main topic of this report. The study emphasizes the necessity of developing new diagnostic techniques in order to quickly and accurately detect dr…
This systematic review both serves as the author’s experience as an intern at Badan Riset dan Inovasi Nasional (BRIN), in the department of Pusat Riset Materi Maju (PRMM), under the guidance of Dr. Nendar Herdianto, M. Si, while being a substitute for a normal internship report. The goal of this internship was to create a systematic review that compiles the previous researches and discusses t…
The exploration of bacterial entry points into plants has been focused on natural openings such as stomata, lenticels, and plasmodesmata. However, the potential role of lateral root (LR) gaps as an entry portal for bacteria remains largely unexplored. This study attempts to investigate the correlation between lateral root number and bacterial colonization, with implications for human health thr…
The new sixth edition of this best-selling introduction to biochemistry maintains the clarity and coherence that so appeals to students whilst incorporating the very latest advances in the field, new worked examples and end of chapter problems and an improved artwork programme to highlight key processes and important lessons.
Were you looking for the book with access to MasteringBiology? This product is the book alone, and does NOT come with access to MasteringBiology. Buy Biology; A Global Approach with MasteringBiology access card 10e (ISBN 9781292008752) if you need access to Mastering as well, and save money on this brilliant resource. This is a Pearson Global Edition. The Pearson Editorial team worked closely w…
Designing Clinical Research has been extensively revised and continues to set the standard as a practical guide for doctors, nurses, pharmacists, and other health professionals involved in all forms of clinical, translational, and public health research. It presents advanced epidemiologic concepts in a reader-friendly way, and suggests common sense approaches to the challenging judgments involv…