Pickering emulsion is an emulsion type where stability is achieved through the use of solid particles instead of surfactants. Jamu, specifically white turmeric (Curcuma zedoaria), is one of the contributors of food by-products in Indonesia and the by-products could be used as Pickering particles. Therefore, this project aimed to evaluate the feasibility of unfractionated white turmeric (Cur…
As the ongoing battle against the escalating challenge of antibiotic resistance persists, pursuing alternative reservoirs for antimicrobial agents becomes crucial. Endophytic bacteria have surfaced as promising contenders for novel antibacterial compounds. Due to the increasing popularity of kratom (Mitragyna speciosa), the Indonesian government encourages the study of potential pharmaceutic…
Lipid-based dairy free RUCF is a ready to use complementary food made with local ingredients. The important quality of the RUCF is the nutrient composition and physicochemical properties, especially the oil separation and PV. With the problems encountered with oil separation in previous study about development of lipid-based dairy free RUCF, this study will reformulate the RUCF with adjuste…
Kombucha is a fermented tea product, which recently innovated by using fruit juices, herbs, and natural extract to create novel taste. This study, explored black sapote (Diospyros nigra) potential as tea replacement to create novel taste and its antioxidant content, which beneficial to reduce non communicable disease. SCOBY act as starter culture, containing AAB and yeast, contributed to ko…
The study addressed the global health concern surrounding folate deficiency by proposing the development of folate-enriched natural snacks using osmotic dehydration, due to its potential to fortify fruits with essential vitamins. The study was structured into preliminary and primary studies. In the preliminary study, a variety of fruits were assessed, and guava was selected as the most suit…
The consumption of apples has shifted towards apple juice due to its convenience and potential for processing. Apples possess strong antioxidant qualities due to the high concentration of polyphenols. However, the processing of apple juice results in a significant loss of antioxidant activities, hence lowering the functional and nutritional value of the product. This study aims to increase …
Capsicum annuum, or chili pepper, is known from traditional medicine to have anti-tumor properties. Recent researches isolated to compound responsible to be Capsaicin, with few researches opposing this notion. Since there are some disagreements as to the validity of this claim, it is important that further tests need to be conducted to prove or disprove the point. Hence, this thesis aimed to…
Osteoporosis is a globally prevalent metabolic bone condition characterized by fragile and low density of bones commonly affecting elderly individuals. It arises from a combination of factors, which include aging, lifestyle choices, genetics and insufficient nutritional resources to sustain optimal bone mineral density (BMD). This condition elevates the risk of bone fractures and is often a…
Preventing severe acne manifestations necessitates early intervention, primarily through reducing inflammation and accelerating wound healing. Facial serums with natural ingredients are increasingly popular due to their minimal side effects and cost-effectiveness, while offering significant potential in acne treatment. Moringa oleifera lam. leaf extract and allantoin are individually recogni…
Malaria remains a significant public health challenge despite advancements in treatment and prevention. The interaction between the malaria parasite and human red blood cells (RBCs) leads to the evolution of RBC disorders that offer protection against malaria. This study aimed to determine the prevalence of RBC disorders from archived DNA samples collected from malaria-endemic and non-endem…
Tempe, a fermented soybean product from Indonesia, showcases how fermentation enhances nutritional value and digestibility. Rhizopus oligosporus, a key starter culture in tempe production, enzymatically enhances carbohydrate, vitamin, and mineral availability from raw soybeans. This process also boosts bioactive compounds such as γ-aminobutyric acid (GABA), recognized for its role as an in…
The turkey berry was first found in 1899 in Columbia County, Florida, and has since spread to at least nine other nations in the Florida peninsula. Turkey berry (Solanum torvum), a nutrient-rich plant, offers significant medicinal and culinary benefits due to its anti-inflammatory, antioxidant, and antibacterial properties. Despite its health advantages, its consumption is limited by its bit…
Pickering emulsions using solid particles to stabilize emulsions are common in the food industry. By-products like rhizome pomace from the herbal beverage jamu are often discarded despite containing valuable compounds. Kaempferia galanga L. (aromatic ginger or kencur) is widely used in jamu Beras Kencur for its health benefits. This research focused on the valorization of aromatic ginger by…
Black sapote (Diospyros nigra), rich in vitamins and antioxidants, is underutilized but promising for value-added products like kombucha. Kombucha’s limited shelf life due to fermentation can be addressed by converting it into powder through spray drying. To achieve acceptable sensorial properties, this study explores probiotic premixes using encapsulating agents (maltodextrin and gum ara…
In certain countries, 10% of the population suffers from non-coeliac gluten sensitivity (NCGS). Additionally, some individuals are affected by gluten ataxia and dermatitis herpetiformis that require lifelong gluten-free diets. However, gluten-free diets often have low fiber content. Bread is known for its flavor and nutritional value, but gluten-free bread typically suffers in texture and qu…
Modern food packaging provides a way to make food safe, reliable, shelf-stable and clean. Edible films, composed of biopolymers that biodegrade along with the food they contain, offer a preservation in structural integrity, and prevention in microbial growth as well as moisture loss. Edible films, crafted from abundantly found ingredients like carrageenan, offer a cost-effective and environ…
There is a growing interest in developing edible films made from natural biopolymers that are favored to enhance the quality of food packaging and meet the demand for sustainable food packaging solutions. This study involved creating a Gelatin-Chitosan (GC) edible film incorporating Lactobacillus rhamnosus GG (LGG) as probiotics to benefit customers' health. Moreover, different concentration…
Utilization of local raw materials such as sago can be an alternative to replace the use of wheat flour in noodle production. However, noodles in general and even sago noodles lack essential nutrients, especially protein and minerals. To address this, fortification processes involving the materials high in protein, anchovies (Stolephorus sp.) and minerals, brown seaweed (Sargassum sp.) are e…
The increasing popularity of pasta is correlated with both modern and busy consumer lifestyles where versatility and convenience become a major key factor in consumer perception and buying decisions. In order to fulfill the market demand, a modern approach to optimize the nutritional value as well as the physical properties of pasta by fortifications has been promoted. One example of the for…
In recent years, meat consumption, particularly convenient products like chicken meatballs increased, driven by changing dietary habits. However, concerns linked to intensive meat production have prompted a shift towards plant-based meat alternatives (PBMAs) that aim to replicate the taste and texture of traditional meats. White button mushrooms (Agaricus bisporus) have become popular for t…
Ochratoxin A (OTA) is a carcinogenic mycotoxin that is widely present in coffee beans and causes public health concern that can widely grow in Indonesia’s temperature. This present study aims to evaluate the OTA contamination level in Robusta coffee beans Indonesia using LC-MS/MS analysis. The age group and consumption rate was determined from the literature as follows: 19-25 years old (h…
As a fruit, apple provides a considerable amount of bioactive compounds, including antioxidant and anti-inflammatory compounds. It is known as rapidly perishable food and is usually processed into apple juice in order to prolong its shelf-life. Conventional apple juice processing utilizes the thermal treatment that may cause the degradation of bioactive compounds. Alternatively, a hurdle of…
A significant amount of seaweed is produced in Thailand. Therefore, the innovation of seaweed must improve the market for harvesters. The hydrocolloid gels in the food industry are becoming more popular due to their ability to improve food quality . Fish cake is a soft, springy processed food made from shredded fish that has been combined with crushed ice and salt. The addition of hydrocoll…
Flour is one of the biscuit ingredient that contribute to the crucial role in biscuit. It contains several main components which include gluten, starch, protein, and water. The presence of gluten in the flour can affect its rheological qualities, which aid in the development of biscuits with both pleasing sensory and appropriate physical properties. However, due to the growing demand for hea…
Jamu is a common practice of Indonesia's traditional drinks to maintain health and immunity made with various natural ingredients from plants and herbs. As for jamu kunyit asam or tamarind acid, just like the name it is made with a combination of turmeric and tamarind. Though there are many ways in combining traditional herbal medicines with the modern form of delights, one of them is gummy …
Indonesia is a major coffee producer with government initiatives targeting the increased demand for Arabica coffee (Coffea arabica). However, Indonesia is a tropical country, which is ideal for the growth of Ochratoxin A (OTA) producers like Aspergillus and Penicillium. OTA is a food safety risk due to its potential for nephrotoxicity and carcinogenicity at high exposure levels. There is sti…
In modern times, consumers are increasingly choosing food packaging that is high quality and sustainable to ensure the safety of the food and minimizing the use of non-recyclable materials that cause negative impact on the ecosystem. As a result, edible film is becoming more popular to improve the quality and safety of food. 3D printing technology offers excellent capability and potential in…
Developing Texturized Vegetable Protein (TVP) from alternative sources is crucial in addressing the concerns associated with soy-based TVP. This study explores the potential of rice bran and mung bean as sustainable and nutritious alternatives to soy in TVP production. The samples were formulated to produce TVP with 55% protein based on the materials: soy (S-TVP) as control, soy and rice bra…
The prevalence of celiac disease has increased significantly over the past decades due to people’s growing knowledge and awareness of the disease, as well as recent advances in its diagnostic tests. This causes the rise of gluten-free foods, including gluten-free bakery goods. Out of all gluten-free flours, rice flour has been recognised as the most suitable flour for gluten-free bakery go…
Pasta is a popular option for many consumers in the world wide. Colored pasta is one creative method to draw consumers' visual. Red fruit oil (RFO) is one of the natural colorants available. RFO has low solubility and sensitive to external conditions. An innovative solution to the problem is using encapsulation to convert oil-based components into powder-based ones. This study aims to examin…
Natural colorant is currently preferred over synthetic colorant due to health reasons. Red fruit oil (RFO) extract becomes a potential orange-red natural source. However, limitation in solubility and susceptibility to external conditions is present. Encapsulation by co-crystallization can be utilized to solve the limitations. During the co-crystallization process, xylitol is utilized to repl…
The cereal bars market is expected to grow annually between 2024 and 2028. Various food industries experimented with many innovations and variations to improve cereal bars. In this study, two edible flowers were used as natural antioxidants as a substitute for synthetic antioxidants while increasing the nutrition values simultaneously. This study is included in one of three studies that inco…
The cereal bars market is expected to grow annually between 2024 and 2028. Various food industries experimented with many innovations and variations to improve cereal bars. In this study, two edible flowers were used as natural antioxidants as a substitute for synthetic antioxidants while increasing the nutrition values simultaneously. This study is included in one of three studies that inco…
Enhancing the utilization of local agricultural and marine products is one of the approach in empowering the local economy. Sago, anchovies, and macroalgae are the examples of underutilized resources in Indonesia, despite their significant potential. In this research, sago flour is used to develop gluten free noodles as noodles are one of the most often consumed food by Indonesians. However…
Jelly drinks are semisolid, readytodrink beverages made from hydrocolloids They are popular but typically lack nutrition, therefore, this study developed healthier variants using real fruit extract, like pineapple juice Hydrocolloids are essential for producing a desirable texture in jelly drinks, and quality is preserved during pasteurization by employing both thermal and nonthermal techniq…
Centella asiatica has been used for medicine, pharmaceuticals, and food supplementation, owing to its high phenolic and flavonoid content, as well as its significant antioxidant activity in the leaves. The need to transform its extract into powder form using microencapsulation is currently emerging, enabling convenience and versatility for various food industrial applications. Spray drying i…
Vanilla (Vanilla planifolia) is prized for its unique flavor, typically consumed as vanilla extract, which requires substantial extraction time using volatile ethanol. Natural deep eutectic solvents (NADES), abundant and non-volatile, have shown solvating ability for bioactive compounds. This study examines the yield of phenolics from vanilla beans based on total phenolic content (TPC), usin…
Malaria, a global health concern, recorded approximately ÃÅÂ million cases and ÇÃÈ,ÁÁÁ deaths in ÃÁÃÁ, with Southeast Asia ranking second in malaria cases Understanding the age structure of mosquito populations is crucial for comprehending malaria transmission dynamics and assessing the impacts of environmental changes and control measures Combating malaria involves control pro…
The crosstalk between natural killer (NK) cells and adipose tissue has gained significant interest due to its critical role in shaping the adipose tissue microenvironment and influencing metabolic homeostasis. It is now widely acknowledged that the activation of NK cells and macrophages in visceral adipose tissue (VAT) during obesity strongly contributes to insulin resistance. However, curre…
Malaria is a major health issue worldwide, with Papua being the epicenter of malaria in Indonesia. To reduce malaria transmission, diagnostic methods have become a crucial pillar in malaria control and elimination. Due to their simplicity, rapid diagnostic tests (RDTs) are used to diagnose malaria in areas lacking expert microscopists, specifically PfHRP2-based RDTs. However, the emergence …
inflammation plays a crucial role in the pathogenesis of various skin conditions such as psoriasis and atopic dermatitis, primarily driven by abnormal cytokine production. This study investigates the anti-inflammatory potential of several synthetic isoflavone-modified compounds (CYR-6811k, CYR-6812l, CYR-6813m, CYR-6815o, CYR-6816p) by examining their effects on cytokine production in THP-1 …
Neutrophils are a type of white blood cell that act as the first line of the innate immune system to protect and against invading pathogens from the human body. Generally, neutrophils are the most abundant cells that play an important role in response to infections through their ability to migrate into affected tissue upon pathogens invasion. The activation of neutrophils are able to engage …
Dengue virus (DENV) infection presents a significant global health threat, especially in Indonesia. This study focuses on identification and genetic characterization of circulating DENV isolates in Timika and Jambi through serotyping, genotyping, and mutation analysis to understand genetic diversity and transmission dynamics. Samples from 119 and 115 suspected dengue patients in Timika and J…
Malaria, caused by Plasmodium parasites and transmitted by Anopheles mosquitoes, is a significant public health issue, particularly in South and Southeast Asia where Plasmodium vivax is prevalent. Understanding the genetic factors influencing mosquito susceptibility to P. vivax is crucial for developing targeted malaria control and eradication strategies. Building on previous findings that …
Influenza A virus (IAV) remains a significant global health concern, prompting ongoing efforts to explore novel antiviral agents. This study investigates the potential of Laportea decumana (Daun Gatal) extract as an antiviral against IAV using A549 cell lines. The objective was to evaluate the extract's impact on cell viability, cytotoxicity, and viral replication dynamics. A series of cytot…
Malaria is a disease caused by infection of the Plasmodium parasite that spreads through Anopheles mosquitoes, which mainly plagues humans living in regions with poor healthcare and countries around the equator. Among the five species capable of causing malaria in humans, Plasmodium falciparum and Plasmodium vivax are noted as the most threatening species, as their manifestations in humans …
Lung is vital to the intricate maintenance of oxygen and carbon dioxide exchange which is regulated by specialised cell lineages. This regulation involves tight coordination of epithelial cells regulated by Non-Muscle Myosin II (NM II). Although adult lung cells are typically quiescent, Acute Lung Injury (ALI) may disturb the homeostasis and cause loss of airway epithelial layer. This will c…