Cancer is a complex disease that involves the growth of cells inside the body. In 2020, more than 10 million people died from cancer worldwide. One of them is brain cancer. Brain cancer itself has higher mortality rate on men rather than women. One of the tools that play pivotal role in detecting cancer is Artificial Intelligence. The Artificial Intelligence helps on analyzing the image pat…
Tempe, a fermented soybean product from Indonesia, showcases how fermentation enhances nutritional value and digestibility. Rhizopus oligosporus, a key starter culture in tempe production, enzymatically enhances carbohydrate, vitamin, and mineral availability from raw soybeans. This process also boosts bioactive compounds such as γ-aminobutyric acid (GABA), recognized for its role as an in…
Malaria is a major health issue worldwide, with Papua being the epicenter of malaria in Indonesia. To reduce malaria transmission, diagnostic methods have become a crucial pillar in malaria control and elimination. Due to their simplicity, rapid diagnostic tests (RDTs) are used to diagnose malaria in areas lacking expert microscopists, specifically PfHRP2-based RDTs. However, the emergence …
Numerous health benefits of medicinal plants are attributed to the abundance of phytochemicals. Among these plants is Elaeocarpus grandiflorus, an endemic tree native to Southeast Asia. The locals utilize its leaves, fruit, endocarp, and bark to treat a variety of illnesses, such as acute intestinal inflammation, diarrhea, and urinary tract infections. This study aims to evaluate and quantif…
In recent years, the cosmetic industry in Indonesia has experienced a sustainable growth due to the emergence of both new local and established brands with strong reputations. Among all, Generation Z represents the predominant demographic shaping the trajectory of the beauty industry in Indonesia. However, the majority of conventional cosmetics have limited regard towards the environmental …
This study explored the relationship between digital marketing (social media marketing and electronic word-of-mouth) and brand equity on purchase intention. Social media is used by the clothing brand Uniqlo as a method of digital marketing due to its large reach to consumers and large user base in Indonesia, specifically the Greater Jakarta area. A survey was conducted through a questionnai…
Customer purchase intention is important to understand and analyze target customers’ preferences as it relates to their desire on purchasing a product. In Indonesia, the popularity of Korean Pop and Dramas impacts many Indonesian women which leads them to imitate and imply Korean cultures in their daily life after gaining attachment to their idols. Due the fact that fans would likely imit…
Cardiomegaly or enlargement of the heart, is a designated umbrella term for various conditions that lead to the enlargement of the heart. Early detection and intervention would increase the chance of survival, however, detection of cardiomegaly is usually done with chest X-rays and might be difficult to do as diagnosis of cardiomegaly involves the detection of subtle and small changes in the he…
Phytoplasmas, which are bacteria that lack cell walls, are known to infect a variety of host plants and spread quickly within them including fruit plants and other types of flora causing significant agricultural losses. Phytoplasmas infect a wide variety of plants, causing irregular plant growth such as phyllody. Phyllody is a developmental transformation in plants that transforms flowers into …
Photorhabdus insect-related toxins A and B (Pir A and Pir B) are two different types of insecticidal toxins that were firstly found in Photorhabdus luminescens. Its homolog, from Vibrio parahaemolyticus, is found to cause acute hepatopancreatic necrosis disease (AHPND) in the shrimp, since it contains plasmid pVA1. When binded together, Pir A and B can exert its effect, because they form a stru…
PT Phapros TBK is a pharmaceutical company founded in 1954, which is now owned and operated under PT Kimia Farma TBK. Research and development falls under the production department, which is one of the 3 main departments in PT Phapros. The Research and development team centers on drug development and analysis, among which Analytical development plays an integral part in the process. During this…
This study investigates the potential of T-cell-mediated immunity in combating SARS-CoV-2, given the concerns about the high mutation rate in the virus's S protein and its potential impact on vaccine efficacy. The prevalent HLA class II alleles in the Indonesian population, namely HLA-DRB1*12:02, HLA-DRB1*15:02, and HLA-DRB1*07:01, play a crucial role in presenting viral peptide antigens to the…
The emergence of SARS-CoV-2 variants is primarily attributed to mutations in the S protein, diminishing the efficacy of existing vaccines that aim to generate antibodies against this S protein. As antibodies become less efficient, T cell-mediated immune response becomes essential in eliminating the virus. Three predominant HLA Class II alleles in the Indonesian population; HLA-DRB1*12:02, HLA-D…
Atypical teratoid rhabdoid tumor (ATRT) is an aggressive pediatric CNS tumor yet lacking standardized therapies while current management standards are not of significant clinical benefit. With the opportunity of accessing the Childhood Cancer Model Atlas (CCMA)’s vast pediatric cancer resources, high-throughput drug screening (HTS) was carried out on the CCMA’s ATRT cohort against the novel…
Fungi, particularly medicinal mushrooms, have been extensively harvested for their natural compounds for alternative medicine because they provide benefits with little to no adverse effects. FIPs, or fungal immunomodulatory proteins, are one that have been extensively studied for their immunomodulatory activities to promote lymphocyte production and subsequently enhance cytokine production. FIP…
The author was doing an internship at PT. Alamii Natura Sejahtera as a research and development intern for 6 months starting from July 2023 – January 2024. The author has several responsibilities including doing research for both optimizing existing product production processes as well as new product development. Additionally, the author also helps the team with the document-making for BPOM-r…
Folic acid is an important vitamin for fetal development and nucleotide and amino acid metabolism. Corn is one of the good sources for folic acid while tempeh fermentation has been reported to increase folic acid content. To concentrate further, membrane filtration is a promising technology. This study aims to understand the effect of microfiltration conditions towards the increase of folic aci…
In recent years, beauty companies have become one of the most succesful business in the world. The cosmetic products are already being produced with advanced technology that can create various new cosmetics products each year. However, the ingredients inside cosmetic formulations become main concerns to many consumers for health concerns, which make natural products in high demand. This study w…
Acne, also known as acne vulgaris, is a chronic inflammatory illness that affects the sebaceous glands and is characterized by the production of erythematous nodules, pustules, and papules, which can scar. Acne is the eighth most prevalent disease, estimated to affect 9.4 % of the global population. Specifically in Indonesia, the prevalence of acne is increasing year by year. Acne has affected …
Snacks are often correlated with bad nutritional content due to high calories, fat, and carbohydrates with low essential protein, vitamins, and minerals. Moringa Oleifera and Lacryma Coix -Jobi L. could be the main ingredient for snacks due to their high fiber content, high antioxidant value, and low glycemic index. Both of the ingredients are easily cultivated and commonly found. However, …
Polyethylene terephthalate (PET) and polyurethane (PU) are two examples of plastics that have integrated seamlessly into our daily lives. The qualities that make plastic so well-known are its low cost, light weight, and strength. However, plastics also can harm the environment when they are no longer in use because they are difficult to break down. The microbial plastic degrading method has …
Environmental problems are increasing public awareness of the importance of protecting the environment. However, this awareness is not directly proportional to the buying behavior of green products. It is caused by several factors: lack of availability, high costs, lack of awareness, perceptions of lack of effectiveness, and greenwashing. Therefore, marketing green products, companies mus…
Erythropoietin is a glycoprotein hormone produced by the kidney. Erythropoietin is a hormone that controls the production of erythrocytic progenitors. Since 1989, erythropoietin (EPO) has been used to treat anemia-related diseases. The formulation of the EPO product was altered in 2004. The occurrence of creutzfeldt-jakob disease (CJD) led to the replacement of the stabilizer, human serum a…
Erythropoietin is a glycoprotein hormone produced by the kidney, which triggers the formation of red blood cells in the bone marrow. However, due to chronic kidney disease, the erythropoietin hormone is insufficiently produced in anemic conditions. Hence, a therapeutic recombinant human erythropoietin (rhEPO) is the alternative way to overcome chronic anemia. Genetically engineered host cells,…
Snack food is one of the fastest growing segments in the food industry, however, often lacks nutritional content. To improve the nutritional content of puffed snacks, especially in protein, this study aimed to evaluate the proximate composition and sensory acceptance of different concentrations (F0 = 0%, F1 = 5%, F2 = 10%, and F3 = 15%) of Moringa oleifera leaf powder (MOLP) supplemented in…
Black sapote is a fruit originating from Mexico that contains high antioxidant activity because of its varying phenolic compounds and micronutrients. Kombucha is one of the beverages that is fermented by a SCOBY to produce a unique and fizzy flavor. A SCOBY consists of acetic acid bacteria, lactic acid bacteria, and yeasts produce some acid for tart and fizzy flavour in kombucha. The effect …
Erythropoietin is a glycoprotein hormone produced by the kidney, which triggers the formation of red blood cells in the bone marrow. However, due to chronic kidney disease, the erythropoietin hormone is insufficiently produced in anemic conditions. Hence, a therapeutic recombinant human erythropoietin (rhEPO) is the alternative way to overcome chronic anemia. Genetically engineered host ce…