A Preliminary Study on the Correlation Between Long Non-Coding RNA MALAT-1 an…

Edition

-

ISBN/ISSN

EP099

Collation

44 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP BI-002

Investigating Hippo-YAP Downstream Gene Expression Under Glutamine and Serum …

Edition

-

ISBN/ISSN

EP092

Collation

37 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP BM-016

Identifying Apo-A1 and Apo-A2 as potential biomarkers in bladder cancer scree…

Edition

-

ISBN/ISSN

EP060

Collation

34 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP BT-008

Industrial Internship Report at PT Dapur Sehat Indonesia (Healthy Go)

Edition

-

ISBN/ISSN

EP041

Collation

31 p. : ill. ; 30 cm.

Series Title

-

Call Number

EP FSN-002

Development of Texturized Vegetable Protein (TVP) from Rice Bran and/or Mung …

Developing Texturized Vegetable Protein (TVP) from alternative sources is crucial in addressing the concerns associated with soy-based TVP. This study explores the potential of rice bran and mung bean as sustainable and nutritious alternatives to soy in TVP production. The samples were formulated to produce TVP with 55% protein based on the materials: soy (S-TVP) as control, soy and rice bra…

Optimizing Mycoprotein Production using Aspergillus oryzae in Soy Whey Substr…

Mycoproteins, that are produced through filamentous fungi fermentation, have gained popularity because of their rich protein content and sustainability as an animal-based protein alternative. However, the cost of the commerciallized mycoprotein exceeds the cost of regular meat. Therefore, scientists are exploring various inexpensive substrates and GRAS fungal strains with high survivability …

The Development of Smart Veggie Snack from Ugly Vegetables

Vegetables are crucial for human health yet the daily consumption is often insufficient to reap their full benefits. 60% of vegetables are discarded due to visual defects which are considered as ugly vegetables. To combat the environmental concern regarding vegetable waste, a vegetable snack bar was developed. Due to its convenience, nutrition rich snack bars such as cereal bars, nutty snac…

Effects of Coriandrum sativum L. Extract on the Cognitive Function and Behavi…

Cognition is an individual’s ability to learn, solve, and appropriately use stored information. Cognitive deficits can manifest in various ways and are commonly caused mainly by age, and other health conditions such as neurodegenerative diseases as well as side effects from certain drugs. Currently, natural supplements using herbal plants have been investigated as cognitive enhancers and b…

Protein Purification of Phytoplasmal Effector Causing Phyllody 1 (PHYL1)

Phytoplasmas, which are bacteria that lack cell walls, are known to infect a variety of host plants and spread quickly within them including fruit plants and other types of flora causing significant agricultural losses. Phytoplasmas infect a wide variety of plants, causing irregular plant growth such as phyllody. Phyllody is a developmental transformation in plants that transforms flowers into …

Identification of Differentially Expressed Genes and Key Pathways Downstream …

Oral Squamous Cell Carcinoma (OSCC) is one of the leading malignant tumors worldwide. The oncogenic long non-coding RNA (IncRNA), LncX, was reported to play a critical role in OSCC progression. To further identify and characterize the key pathways and genes downstream of LncX, we will integrate online datasets and bioinformatic analysis to investigate the expression pattern of LncX in OSCC and …

Validation Of Predicted Sars-cov-2 Nucleocapsid Protein Peptides (np104-122, …

This study investigates the potential of T-cell-mediated immunity in combating SARS-CoV-2, given the concerns about the high mutation rate in the virus's S protein and its potential impact on vaccine efficacy. The prevalent HLA class II alleles in the Indonesian population, namely HLA-DRB1*12:02, HLA-DRB1*15:02, and HLA-DRB1*07:01, play a crucial role in presenting viral peptide antigens to the…

Immunogenicity Validation Of The Predicted Hla Class Ii T-cell Epitope from S…

The emergence of SARS-CoV-2 variants is primarily attributed to mutations in the S protein, diminishing the efficacy of existing vaccines that aim to generate antibodies against this S protein. As antibodies become less efficient, T cell-mediated immune response becomes essential in eliminating the virus. Three predominant HLA Class II alleles in the Indonesian population; HLA-DRB1*12:02, HLA-D…

Sensorial Properties and Physical Characteristics of Vegan Rendang using Shii…

Lifestyle has been a factor that highly influences human health and life quality. The rising trend of healthy lifestyle has been one of the supporting factors in current changes in food consumption pattern. One of the trends that can be seen to be constantly rising over the past year in the food industry are vegan and plant based food. Alternative plant based food products that imitate real mea…

THE EFFECT OF MALTODEXTRIN AND WHEY PROTEIN ISOLATE IN THE ENCAPSULATION OF …

Red fruit oil (Pandanus conoideus Lam.) is a carotenoid rich oil originating from Papua and a potential source of natural food colorant. Due to its volatile form, a preservation method through encapsulation by spray drying was applied in this study. Maltodextrin and whey protein isolate were used as carrier agents, five formulations were made at different concentrations (formula A (MD only),…

Investigation of Cricket Powder and Nutritional Yeast Application in Noodle a…

Noodles are a staple food in Asia. However, since it is made using wheat flour which is high in carbohydrate, protein enrichment by adding other ingredients like cricket powder and nutritional yeast can be done. This study aimed to increase the protein content in noodles by incorporating cricket powder and nutritional yeast with different substitution levels (10, 15, and 20%) towards the …

Expression and Purification of A Bioactive Recombinant Fungal Immunomodulator…

Fungi, particularly medicinal mushrooms, have been extensively harvested for their natural compounds for alternative medicine because they provide benefits with little to no adverse effects. FIPs, or fungal immunomodulatory proteins, are one that have been extensively studied for their immunomodulatory activities to promote lymphocyte production and subsequently enhance cytokine production. FIP…

Physiccochemical, Textural and water soluble Protein Analysis of Overripe Tem…

Overripe tempeh is tempeh that had been fermented for 2 – 5 longer than fresh tempe wherein mold fermentation ceases and taken over by bacterial fermentation. It is commonly used in traditional Javanese cuisine as a basic flavoring agent. Most of the studies of tempeh range from microbiology, chemical and nutritional changes, functionality and its sensorial aspect but information on overripen…

Effect of Whey Protein and Gum Arabic Ratios on Survivability and Physicochem…

Pediococcus acidilactici has gained research interest due to its potent probiotic characteristics. However, it has low survivability in the gastrointestinal tract (GIT). Thus, spray drying is commonly used to improve its survival. Although current studies obtained high spray drying encapsulation efficiency, further evaluation of its survival during GIT and viability during storage is no…

Next-Generation Sequencing and Prediction of T-cell Epitopes from Structural …

The COVID-19 global pandemic caused by SARS-CoV-2 has been going on for almost two years and has negatively impacted the global population. The same as other viruses, SARS-CoV-2 is continuously mutating to adapt to the environment, and this may result in negative impacts, such as an increase in virus transmission, virulence, and even resistance to vaccines. Hence, questions regarding whether th…

The Role of Receptor Activity Modifying Proteins (RAMPs) in Pancreatic Cancer

Pancreatic Cancer (PaCa) is the 5th leading cause of cancer-related death in the UK. Understanding the signalling behind PaCa development is essential to create novel treatment for PaCa. RAMPs are family of single transmembrane domain proteins. The interaction between RAMP and GPCR give rise to AM receptor complex. AM is a hormone that has been shown to promote progression of various tumou…

Optimisation of Crystal Formation for the recombinant Fungal Immunomodulatory…

Background: FIP-Lrh is a fungal immunomodulatory protein from Tiger Milk Mushroom with immunomodulatory and cytotoxic properties. Its biological properties can be further elucidated with the availability of a crystal structure. However, crystal structures from only four FIPs have been reported so far. As such, previous study at UCSI and MGVI on rFIP-Lrh crystallisation under two conditions …

Immunoinformatics Approach to a Multivalent and Multi-epitope Oral Vaccine De…

The currently available COVID-19 vaccine is thought to be sufficient in protecting against SARSCoV-2 infection, whilst the constant mutations of SARS-CoV-2 and the failure of the vaccine mto evoke protective mucosal immunity have remained problems. This condition has brought forward the idea of targeting nucleocapsid (N) protein as a more conserved region of SARS-CoV-2, in addition to the spike…

Role of Integrated Stress Response in Mediating Mitochondrial Unfolded Protei…

The integrated stress response (ISR) is one of the most conserved cellular stress responses during mitochondrial dysfunction. The keys in the activation of ISR are the phosphorylation of eIF2α and subsequent induction of ATF4. The phosphorylation of eIF2α is caused by the activation of four specific serine/threonine kinases, which are Heme Regulated Inhibitor (HRI), Protein Kinase Ribonucleic…

Evaluation of Heat Denaturation and Adsorption-Desorption as a Method for Con…

A preliminary antimicrobial assay showed the antimicrobial activity of P. acidilactici but the SDS-PAGE did not reveal pediocin, an antimicrobial peptide produced by Pediococcus strain. The efficient downstream processing of P. acidilactici fermentation is studied to analyze pediocin. This research is conducted to assess the compatibility of different methods in concentrating pediocin in th…

Immunoinformatics Pipeline for Multi-Epitope Peptide Vaccine Design Based on …

COVID-19 were identified as viral diseases which was caused by the Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2). The SARS-CoV-2 are known to be the family of coronaviridae. As we all know that patients that were infected by the COVID-19 has risen significantly since the very early outbreak that happens in the early December 2019 specifically at Wuhan, China. Researc…

Investigation on the Removal of Depth Filter For an Effective Human Recombina…

Erythropoietin is a glycoprotein hormone produced by the kidney, which triggers the formation of red blood cells in the bone marrow. However, due to chronic kidney disease, the erythropoietin hormone is insufficiently produced in anemic conditions. Hence, a therapeutic recombinant human erythropoietin (rhEPO) is the alternative way to overcome chronic anemia. Genetically engineered host cells,…

Expression and Purification of PiuA Recombinant Protein Using Additives For P…

Glycoconjugate vaccine involved the conjugation of polysaccharides from a pathogen and a protein carrier whereas pneumococcal conjugate vaccine (PCV) is one of the examples. The pneumococcal diseases caused by Streptococcus pneumoniae can be tackled by the PCV, which was produced by chemical conjugation. Due to the challenges in the production such as polysaccharide extraction and purificat…

The Effect of Soy Protein Isolate and Konjac Glucomannan Hydrolysate Towards …

This study took plant-based fishball (PFB) as a seafood analog to apply the glycated solution of soy protein isolate (SPI) and konjac glucomannan hydrolysate (KGMH). The glycated solution was prepared through the wet-heating Maillard reaction, followed by assessing the stability index of the solution and the incorporation of the glycated solution to the plant-based fishball. The PFB were ca…

Evaluation Of Protein And Energy Intake From Soy Food Consumption In Indonesi…

Despite the availability of various soy products in Indonesia, research on soy consumption in the general population is limited, with existing studies mainly focusing on specific subgroups. A cross-sectional study was conducted involving a representative sample of 100 Indonesian adults, who recorded their food consumption using weighed food records for 3 days. Nutritional data was calculate…

Polyphenol and Sensitive Protein Reduction During Filtration of Different Bee…

PT Multi Bintang Indonesia is a multinational level company under Heineken® group, specializing in beer production. The internship was taken place from 30 th of January to 15 of May 2023 in Quality Control and Quality Assurance Department that is located at Tangerang brewery. Total polyphenol and sensitive protein in beer is promoted by malt and hops. However, presence of haze active poly…

Assessment of Soy (Glycine max L.) Intake Using Semi-Quantitative Food Freque…

Soybean (Glycine max L.), a species of legumes, is a well-known source of highquality plant-based protein widely cultivated in Asia. An intake of ≥25 g/day of soy protein has been reported to be associated with a lot of health outcomes. In Indonesia, soybean is one of the most favored protein sources. In order to understand the frequencies and amounts of macro- and/or micronutrients from …

Plant-Based Meat Product Development: Patty and Nugget

Plant-based meat popularity has been trending in these past couple of years. This trend can be aributed to a growing awareness of plant-based diets' environmental impact and potenal health benefits. The trend also affects the development of plant-based meat products in various countries. This study aimed to develop plant-based products in …

Assessment Of Microbial and Chemical Properties Of Red Sorghum Kombucha Products

There is a possibility of sorghum utilization as a food product in the Indonesian Market. In reality, some parts of the country already started to produce Sorghum to provide food and animal feed requirements. This is due to the nutritional content in sorghum that is said to be high in carbohydrates, protein (10%), fiber, and a rich source of amino acids. However, a large portion of compon…

The Utilization of Flavors to Mask the Off-Notes of Pea-Protein Milk

The study was conducted during the author's internship as a Creative and Design Intern at IFF - PT Essence Indonesia. IFF is a key supplier in the flavors and fragrances market, and the author had the opportunity to use masking and vanilla flavor for her project. Non-dairy milk alternatives are growing in popularity and there are more available options such as plant-based milk. In this proj…

The Effect of Freezing Time Variation in Freeze-Drying on Protein Characteris…

esenchymal stem cells (MSCs) have been long studied and developed as a regenerative medicine supported by their secreted bioactive molecules called secretome or MSC-secretome (MSC-S) that contain soluble factors and extracellular vesicles (EVs). Unlike the MSC-based therapy that utilized the whole cells, secretome is a cell-free therapy that would ease the future treatment development as it …

Investigation on the removal of Depth Filter for an effective Human Recombina…

Erythropoietin is a glycoprotein hormone produced by the kidney, which triggers the formation of red blood cells in the bone marrow. However, due to chronic kidney disease, the erythropoietin hormone is insufficiently produced in anemic conditions. Hence, a therapeutic recombinant human erythropoietin (rhEPO) is the alternative way to overcome chronic anemia. Genetically engineered host ce…

THE DEVELOPMENT OF PROTEIN BAR AS THE ALTERNATIVE PROTEIN SOURCES FOR ATHLETE…

PT Nutrisi Harapan Bangsa is a company engaged in the sport nutrition industry which provides products that design specifically for athletes and sports persons, as distinctive nutrition is required for them. PT Nutrisi Harapan Bangsa sold the products under the name of Strive. The creation of this company was driven by the desire to have nutrition dense, delicious and affordable sports food…

Protein Expression and Purification of Taq Polymerase

The development and application of molecular diagnostic technologies has triggered a revolution in infectious disease diagnosis and surveillance over the years. The ability to deliver a quick, specific, reliable, cost-effective, and straightforward alternative is one of the advantages of using molecular diagnostics. Taq polymerase is an example of an enzyme that is required in molecular di…

Coffee Plant Proteomics Annotation for Natural Products

Indonesia was the fourth largest coffee producer in the world in 2014, thus it is safe to say that Indonesians love to drink coffee. The consumption of coffee has its health benefits and its risks, one of the risks is mostly related to cardiovascular diseases. One of the diseases is hypertension which is considered “the silent killer” as it is a serious condition w…

Effect of Enzymatic Pretreatment using Viscozyme L to the Functional Properti…

Quinoa is a grain found in the plant Chenopodium quinoa Willd. which is resistant to many environmental stresses and is able to grow in tough conditions with nutritional value which include balanced amino acid composition compared to other plant/grain based protein. The protein of the quinoa itself can be found in protein bodies of the seed radicle and endosperm which are bound to starch or…

Immunoinformatics Analysis to Design a Multiepitope Peptide-Based Breast Canc…

In 2020, breast cancer incidence in Indonesian women had become the highest among other cancers. There are different approaches to combat this disease; one of them is immunotherapy which focuses on utilizing the body’s immune cells to eliminate and evoke an immune response against cancer. This study aims to develop a multi-epitope peptide-based vaccine targeting Mucin 1 (MUC-1) and Matrix Met…

The Potential of Gynura Divaricata Interaction with Malaria Blood-Stage Prote…

Malaria is a parasitic infection affecting people worldwide, with P. falciparum being the most dangerous. Identifying more validated asexual and sexual blood-stage drug targets may be key to malaria eradication and control for a variety of reasons. Gynura divaricata (Lour.) Merr. is an Indonesian medicinal herb that contains various natural compounds with antibacterial and potentially antim…

Physicochemical Stability of Co-crystal RFO-colored Beverage Added with Diffe…

Red fruit is an indigenous plant that grows mainly in Papua that is commonly used as a natural colorant but it has several limitations. Co-crystallization was chosen to be the suitable encapsulation method to improve the stability and solubility of RFO. Sodium caseinate (NaCas) were prepared as the emulsifier in the crystallization to improve the stability of RFO. The pure RFO, co-crystalli…

Encapsulation of Red Fruit (Pandanus conoideus Lam) Oil by Co-crystallization…

Red fruit oil is a native plant found in Papua Island with a high carotenoid concentration, thus it is considered a promising source of natural food colorant. However, as it is present in the form of oil, it is prone to oxidation and hard to dissolve in water. Hence, an encapsulation method such as co-crystallization is required. Sodium caseinate, WPI, and SPI were used in this study as a pr…

Lipoprotein Lipase and Cholesteryl Ester Transfer Protein Genes-Dietary Fat I…

India has the second-highest type 2 diabetes mellitus (T2DM) due to the South Asian phenotype, poor lipid profile, and unbalanced dietary pattern. Evidence has been discovered that single nucleotide polymorphisms (SNPs) in the lipoprotein lipase (LPL) and cholesteryl ester transfer protein (CETP) genes are linked to differences in lipid levels in response to dietary intake. Hence, this revie…

COMPOSITION AND PROTEIN YIELD ANALYSIS OF UNTREATED AND VISCOZYME L PRE-TREA…

Quinoa is a potential alternative to accommodate increasing demand of protein isolate as they have high nutritional value, however, quinoa has relatively low protein content. This problem could be combated through enzymatic pre-treatment. This study aims to observe the difference and similarity of composition of quinoa protein isolate that are and are not pre-treated with Viscozyme L. White qui…

The Effect of Carrier Agents in the Encapsulation of Red Fruit Oil (Pandanus …

Red fruit oil (Pandanus conoideus Lam.) is a great source of carotenoid pigment for its potential utilization as a coloring agent. In order to preserve carotenoids and improve its stability over storage, encapsulation using freeze drying was performed in this study by using two different carrier agents, maltodextrin (MD) and whey protein isolate (WPI), solely and in blends at different concentr…

EFFECTS OF SOY PROTEIN ISOLATE AND METHYLCELLULOSE ADDITION IN EMULSION TOW…

Cultured meat is a novel eco-friendly product which currently face specific challenges such as consumer behavior which were influence by knowledge and attitude & belief. Therefore, this research aims to assess the consumer knowledge, attitude & belief, and behavior towards cultured meat. The assessment of demographic characteristics, consumer knowledge, attitude & belief, and behavior were cond…

Investigation of Cricket Powder and Nutritional Yeast Application in Noodle a…

Noodles are a staple food in Asia. However, since it is made using wheat flour which is high in carbohydrate, protein enrichment by adding other ingredients like cricket powder and nutritional yeast can be done. This study aimed to increase the protein content in noodles by incorporating cricket powder and nutritional yeast with different substitution levels (10, 15, and 20%) towards the physic…

Protein metabolism and nutrition

Edition

-

ISBN/ISSN

0408706694

Collation

ix, 515 p. : ill. ; 24 cm.

Series Title

-

Call Number

636.08 Col p