The increasing popularity of pasta is correlated with both modern and busy consumer lifestyles where versatility and convenience become a major key factor in consumer perception and buying decisions. In order to fulfill the market demand, a modern approach to optimize the nutritional value as well as the physical properties of pasta by fortifications has been promoted. One example of the for…
Glioblastoma multiforme (GBM) is a highly aggressive glioma that is reported to exhibit elevated glutamine uptake and metabolism, termed as glutamine addiction, often associated with poor patient prognosis. Recently, a preliminary study identified glutamine transporter SLC7A8 to be highly upregulated in resistant GBM and associated with poor prognosis, with results intriguingly showing dist…
Humans have been co-existing with a whole population of microbes, where trillions of different microbes are living inside the human GI tracts as a commensal gut microbiota. This condition provides a mutual relationship where the gut microbiota serves as a natural protection for the intestinal tract homeostasis. Nevertheless, the human intestinal tract is constantly exposed to environmental …
Cancer remains a global health challenge in need of precise, cost-effective, and scalable research tools for comprehensive investigations. Spheroid-based methodologies emerge as reliable, easily adaptable, and highly scalable techniques, offering an improved representation of in-vivo conditions compared to conventional 2D cell cultures. This study utilizes the Huh-7 cell line to generate hep…
Indonesia is striving for a greener and cleaner future, and is pushing for the commercial application of biofuels. Currently Indonesia is focused on palm-oil based biofuels, but it comes with many negative impacts and challenges. Hence, it is necessary to improve upon biofuel production technology. Shifting towards third generation microalgal biofuels is an attractive option, as microalgae h…
As the human population grows, the demand for organoleptic properties in food has linearly increased, including the use of harmful synthetic colorant. Therefore, carotenoids, as a secondary metabolites and natural compounds, can be used as an alternative to natural food preservatives. They are also attributed to antioxidant properties which are beneficial for human consumption and health. T…
Indonesia's heavy rice import reliance raises food security concerns. Millet, rich in carbohydrates, antioxidants, vitamins, and minerals, can be used in pasta with edamame flour for enhanced protein and fiber. By combining both ingredients, it fills the gap of previous research by incorporating different legumes types and combining gluten-free ingredients with aids in informed product deve…
Fortifying low-fat milk with nutrients essential for overall health, mainly gut health and immunity, is crucial as these can supply the substances required to keep the body's immune system functioning properly. Examples include adding fiber and vitamin premixes (a combination of A, E, and C). However, to meet consumer demand for variety and a distinctive flavor experience, flavored milk was …
Dry Eye Disease (DED) presents a significant challenge in ophthalmic care, necessitating effective preservative-free eye drop formulations. This study investigates the influence of process variables and polymer types, namely Hydroxypropyl Methylcellulose (HPMC) and Xanthan Gum, on critical quality attributes (CQAs) of Polyethylene Glycol-Propylene Glycol (PEG-PG) eye drops, emphasizing a Qua…
Rinse-off hair and body care products are essential for maintaining the health and hygiene of hair and skin, formulated with surfactants to cleanse and improve appearance. Some of these products contain ingredients that provide humectants, emollients, conditioning agents, et cetera, which modify the fundamental functions of the products. However, the current formulations of these products o…
Green supply chain management has been a popular approach for many businesses to respond to many environmental issues, such as climate change, loss of biodiversity, resource depletion, greenhouse emissions, and climate change. This research aims to explore the effects of supply chain management on organizational sustainability performance and how it affects the products produced by the manu…
The widespread trend of global industrialization in Indonesia has resulted in the depletion of natural resources and environmental destruction. Indonesia has been undergoing recent changes in accordance with the 2030 agenda to potentially achieve the Sustainable Development Goals and reduce carbon footprint. The pivotal role of an organization’s Human Resource (HR) Department in cultivatin…
This subchronic toxicity study assessed the delayed toxicity and reversibility of fennel extract in male and female mice. To ascertain any delayed toxicity and potential for recovery, a separate satellite group received oral doses of fennel extract at a dose of 1000 mg/kg/day of body weight for a duration of 90 days, followed by 28-days with no treatment. There were no abnormalities observed in…
Shampoo is a type of hair care product that is used to clean the scalp and remove the dirt. Not only for humans, shampoo is also used for animals, especially dogs. However, different from human shampoo, dog shampoo tends to be milder due to the different pH and sensitivity of dog’s skin compared to human skin. It is important to formulate a shampoo that has good properties for dog characteris…
Foeniculum vulgare or known as adas in Indonesia is a medicinal plant that belongs to the umbelliferae family. It has a lot of pharmacological properties such as antiviral, antimicrobial, antioxidant, anti-inflammatory, anti-anxiety, gastro-protective, estrogenic-like, cardiovascular, lipid-lowering, anti-mutagenic, anti-diabetic, anti-cancer activity, hepatoprotective, and memory-protective ch…
Apis mellifera or honey bee is the most crucial pollinator globally, providing 50% of global crop pollination. However, bee colony loss is increasing and one of the causes is American foulbrood disease (AFB), a disease that kills honey bee larva. Paenibacillus larvae, a gram positive bacteria is the causative agent of AFB, it can produce spores that are able to survive in extreme heat and c…
Tuberculosis caused by an obligate aerobic bacteria known as Mycobacterium tuberculosis is one of the most lifelong diseases that has been infecting humans worldwide; Indonesia is one of the countries that has the highest prevalence of tuberculosis. The bacteria itself possesses an atypical cell wall structure that protects them from harmful drugs. With the inconsistent, prolonged drug treatmen…
Packaging preserves the quality of the finished product for consumption, storage, and transportation, making it one of the most crucial steps in producing food goods. In cheese products, molds can contribute to odor, distinctive flavor, consistency, and appearance and increase shelf life. However, some species might cause product spoilage. Thus, high-quality packaging is required to prevent mol…
K-Wave has been popular for Indonesians in various forms of entertainment and culture including Korean Food from early 2000s. Kimchi has become one of their favourite dishes. Kimchi products can be easily found in the Indonesian market in numerous forms such as instant noodle seasoning. However, the innovation of kimchi flavor in the instant noodle seasoning is lacking, therefore, the idea of â…
In the freeze-dried snack and food market, PT Sadjian Bumi Indonesia is a small business that specializes in compact and quick food items and offers products with extended lifespans. Under the brand name Sadjian, PT Sadjian Bumi Indonesia offered the products. The concept of PT Sadjian Bumi Indonesia's product is to offer a distinctive, easy-to-consume food item that is also more nutritional. S…
Currently, the demand for sustainable platforms to address environmental problem is arising. Biodiesel is an eco-friendly alternative for regular diesel as it has many advantages, and the most important thing is derived from environmental-friendly source, such as microalgae. Several microalgae are known for being able to synthesize lipids and even higher concentration. Newly microalgal strains …
During the internship, the main project done is the Water for injection hold time study at room temperature. Water for injection is a type of pure water used in pharmaceutical production that has been treated using distillation. Water for injection is used for cleaning equipment, mixing solutions, and validating cleaning. The study aims to investigate the condition of water for injection for…
Red fruit oil (Pandanus conoideus Lam.) is a carotenoid rich oil originating from Papua and a potential source of natural food colorant. Due to its volatile form, a preservation method through encapsulation by spray drying was applied in this study. Maltodextrin and whey protein isolate were used as carrier agents, five formulations were made at different concentrations (formula A (MD only),…
This study aimed to develop a lipid-based paste form of Ready-to-Use Complementary Food (RUCF) using locally available ingredients, while investigating the physicochemical changes during 21 days of storage. Three formulations were proposed and assessed using B one touch viscometer for viscosity, CS410 handheld colorimeter for color, pawkit water activity analyzer for water activity, and e…
An expensive Vanilla planifolia Andrew. Var. Vania 2 is commonly propagated using a stem cutting technique which is associated with low propagation rate. A method of callus regeneration was assessed in this experiment to increase the yield of vanilla plants by utilizing different concentrations and combinations of BAP and NAA supplemented into the MS media. The objectives of this experi…
The global food industry grapples with significant waste and loss, with more than one-third of total food production. This waste, extending from agricultural production to consumption, poses environmental and disposal challenges. Postharvest losses, particularly in fruits, contribute significantly, with over 60% of cultivated land crops going to waste. Addressing this issue is crucial for econo…
The Indonesian culinary landscape is characterized by a rich variety of flavors and cooking techniques, with the renowned dish "Pempek" standing out as a culinary masterpiece. Pempek is a meticulously crafted fishcake, where the thoughtful combination of fish, flour, and seasonings results in a harmonious blend of texture and taste. Beyond its culinary prowess, Pempek goes beyond mere gastronom…
Temozolomide (TMZ) stands as the primary chemotherapy choice for glioblastoma multiforme (GBM), yet resistance frequently emerges in patients, leading to tumor recurrence and worsened prognoses. A recent study reported upregulation of glutamine and glutamate transport and metabolism in TMZresistant GBM in silico, particularly highlighting the upregulation of Gene X. Given the reported glutamine…
The most respected nutrition text for more than 50 years, Krause's Food and the Nutrition Care Process delivers comprehensive and up-to-date information from respected educators and practitioners in the field. The latest recommendations include the new MyPlate guide, the Dietary Guidelines for Americans 2010, new and expanded chapters, and a large variety of tables, boxes, and pathophysiology a…
"The study delves into the characterization of bacterial communities within Takakura composting. Takakura composting is a method integral to organic waste management, and serves as the focal point for understanding microbial dynamics during decomposition. The research aims to make takakura compost with two different compositions and characterize the bacterial community in the Takakura compo…
Phosphorous acid is a safer and more environmentally friendly alternative to commercial pesticides as it contains a component called phosphite that exhibits fungicidal and bactericidal activities. Foliar spraying and soil drenching are two methods of exposure to phosphite that must be carefully conducted because an excessive amount of phosphite is toxic to plants, impairing their growth and dev…
This research project addresses the challenge of food waste at Hangry Indonesia, a cloud kitchen restaurant. Focusing on rice, a staple in their menu, the study aims to create a sustainable system to reduce food waste when sales fall short of targets. Additionally, the project explores the impact of reheating frozen rice on texture, specifically addressing issues such as browning and hard…
This study highlights the environmental consequences of landfill buildup while addressing the issue of insufficient food waste management in Indonesia and the 1.3 billion yearly instances worldwide. The study focuses on the Takakura Composting Method (TCM), which combines fermentative microorganisms and locally created materials to provide a sustainable household-scale solution. The Takakur…
hellfish allergy is one of the highest prevalence allergies in the world, accounting for 7.7% of the population including Indonesia. Thus, the development of T cell epitope and B cell epitope based vaccines play an important role in future prospects for alternative treatment for allergy. The vaccine aims to induce the immune system so it will not react towards the allergen though the body al…