Screening of Isoflavone-Modified Compounds as Potential Therapeutic Agents to…

inflammation plays a crucial role in the pathogenesis of various skin conditions such as psoriasis and atopic dermatitis, primarily driven by abnormal cytokine production. This study investigates the anti-inflammatory potential of several synthetic isoflavone-modified compounds (CYR-6811k, CYR-6812l, CYR-6813m, CYR-6815o, CYR-6816p) by examining their effects on cytokine production in THP-1 …

Exploring the Impact of Andaliman (Zanthoxylum acanthopodium) Fruit Crude Ext…

This study investigates the anti-inflammatory properties of Andaliman (Zanthoxylum acanthopodium DC.) fruit extract on inflamed human keratinocytes (HaCaT cells). The phytochemical profile of Andaliman reveals a high content of terpenoids from the Salkowski test, which inhibits the NF-κB signaling pathway, thereby suppressing pro-inflammatory cytokine production. The study demonstrates a s…

In Vitro Study of Sunscreen Product Towards UV-B and Protection Through Measu…

Ultraviolet light is a type of light that is exhibited from the sun. Ultraviolet is divided into 3 types, including UV-A, UV-B, and UV-C light. These Ultraviolet light might cause several adverse effects including skin and eye damage. Hence, the application of sunscreen is important to prevent the damage induced by UV exposure. Sunscreen is divided into several types including cream, stick, …

The evaluation of anti-aging properties of Serum product on primary human der…

The skin provides conspicuous signs of aging, and many people are willing to spend a grand amount of money to keep their youthful appearance. Nowadays, treatments to delay the signs of aging in the skin are available, but most people favor the use of topically applied serum, due to its high concentration of active ingredients and comfortable finish product. This project highlights the evalu…

Investigating the Effects of Litsea oppositifolia Stem Extract on HaCaT Cell …

Skin aging is an inevitable process in which the skin declines in quality which can be affected by intrinsic and extrinsic factors. One of the important factors contributing to skin aging is the accumulation of ROS (Reactive Oxygen Species). The ROS model was often used to study the effect of compounds that could affect skin aging and the most commonly used ROS model is H2O2, has been associate…

Acne Prone Skin Consumers Toward the Importance of Moisturizers and The Types…

Acne, also known as acne vulgaris, is a chronic inflammatory illness that affects the sebaceous glands and is characterized by the production of erythematous nodules, pustules, and papules, which can scar. Acne is the eighth most prevalent disease, estimated to affect 9.4 % of the global population. Specifically in Indonesia, the prevalence of acne is increasing year by year. Acne has affected …

Factors Influencing Customer Satisfaction when Buying Skincare Products throu…

The number of TikTok users in Indonesia, which has grown rapidly in recent years, has opened up business opportunities to reach customers anywhere and at any time. This study examines the factors that affect customer satisfaction when purchasing skincare products on TikTok social media in Jakarta. In addition, we will adopt the factors influencing the customer satisfaction model from rese…

The Utilization of Flavors to Mask the Off-Notes of Pea-Protein Milk

The study was conducted during the author's internship as a Creative and Design Intern at IFF - PT Essence Indonesia. IFF is a key supplier in the flavors and fragrances market, and the author had the opportunity to use masking and vanilla flavor for her project. Non-dairy milk alternatives are growing in popularity and there are more available options such as plant-based milk. In this proj…

Formulation and Evaluation of Antioxidant Cream Containing Morinda citrifolia…

Skin issues are common problems in daily life. The oxidative effect by exposure to UV radiation and pollution causes skin inflammation and premature aging. Nowadays, the cosmetic industry has shifted toward usage of natural products. The Noni fruit (morinda citrifolia) used as food and medicine, prevents and treats a variety of diseases. The problem with the extract is their poor penetr…

Early detecon of Superficial Fungal Infecon in Rumah Merah Puh Community and…

Skin fungal infecon is the infecon caused by dermatophytes and superficial mycoses. This infecon is a common public health problem, especially in marginalised children. Many of them live in unsanitary environments and do not have enough educaon about health and hygiene. This causes a lack of awareness of this infecon and increases the ris…

Skincare and Bodycare Product Line Ideation, Innovation, and Development with…

The personal care market in Indonesia is promising, but the surge of food and plastic waste, alongside the perception that international brands are better than local brands in terms of safety, efficacy, and/or quality have become the main issues that could hinder the growth of these manufacturing industries. Production of new skincare and/or bodycare products with a unique selling point (US…

Analysis of XR Skin Product Active Ingredients Effect on the Skin Physiology …

Skin types condition can cause different skin problems. Skin types can be divided into 2 which are dry and oily skin. Dry skin is more prone into having wrinkles due aging and less production of collagen on the skin. Aging of the skin can be caused by long exposure to ultraviolet light. Skin aging can be combated with antioxidant compound. This compound able to scavenge free radical which s…

In Vitro Cytoprotective Study of Litsea oppositifolia Stem Extract Against Hy…

Skin aging is an inevitable natural process in which the skin undergoes changes due to exogenous factors (UV, pollutants, and toxins) and endogenous factors (genetic mutation, metabolism, and hormones). Due to the nature of the process, the demand for anti-aging cosmetic products has increased, rendering the need for alternatives to develop more anti-ageing products. One factor that promote…

Analysis of Awareness and Quality of Life Towards Superficial Fungal Infectio…

Skin fungal infection has been one of the most lethal infections if not treated properly as they have the ability to invade other systems. Yet, this infection is often neglected especially in Indonesia. Hence, this project aims to produce an educational booklet while also to do socialization to increase awareness towards fungal skin infection in three communities in Jakarta and Bekasi. Parti…

Inflammatory Evaluation of a topical Moisturizer Product on Human Keratinocyt…

Skin barrier disorder is a condition whereby the skin is incapable of preventing the penetration of exogenous stimuli. As a result, inflammation are also elevated in an effort to eliminate these materials, resulting in increased sensitivity towards exogenous material. Treating this dysfunction can be achieved using topical application of prescriptions such as moisturizers that can tone down…

The Evaluation of Moisturizer Effects Towards Skin Barrier Integrity Using Ge…

Skin barrier integrity is mainly maintained at the outermost layer of the skin, which is cons????tuted by suppor????ve molecules. Ceramide cons????tutes the largest lipids amount in the intercellular lipid matrix. Filaggrin is a protein involved in the stratum corneum mechanical integrity maintenance. Hyaluronic acid mainly acts as a humectant to maintain hydra????on. Nowadays, moisturizers…

In vivo Pilot Study of Moisturizer Evaluation and Correlation between Ceramid…

Stratum corneum (SC) is the outermost layer of the skin surrounded by the lipid matrix and forms a multilamellar barrier for the skin. The main function of this layer is to prevent the permeation of external molecules into the epidermal and dermal layers and prevent excessive water loss from the skin (van Smeden & Bouwstra, n.d.). As the lamellar barrier's major lipid component, ceramides ar…

The Correlation Analysis between the Expression of Filaggrin, Involucrin, Lor…

A healthy and moisturized skin is the result of a healthy and functioning barrier function. The barrier function mainly consists of the CE layer of the epidermis, which is formed by the cross-linking of FLG, IVL, and LOR genes that are catalyzed by TGM-1 gene. However, due to many factors, the moisture and water content in the skin may be altered; thus, resulting in dry skin. The usage of moist…

Determination of Anti-Aging Properties of Cosmetic Toner Product on Primary …

Skin is the largest organ in the body and is continuously exposed to various chemicals, radiation, and pollutant. Therefore, along with the increase in age, physical signs of skin aging become apparent. Many individuals reach for various anti-aging cosmetics to restore the normal appearance of the skin, as beautiful skin confers the perception of a healthy individual and increases the social va…

Investigation of a Moisturizer to Skin Moisturizing Function Efficacy Through…

The corneocytes hold a role in skin moisturizing due to Natural Moisturizing Factor (NMF) possession. This hygroscopic component, mainly composed of free amino acids, is the result of filaggrin protein degradation and is proportionally produced as the skin gets moisturized. Moisturizer is thought to improve skin moisture through its ingredients. Previous research experimented with skin gene exp…

Nerve Sedation Effect of a Sensitive Skin Moisturizer towards Human Keratinoc…

Sensitive skin, which can be indicated by unpleasant feelings to the skin, such as burning, tingling, stinging, and itching, has become a growing concern in the last few decades. This situation is mainly due to the increasing level of air pollution, global warming, and the use of skin products that can trigger and worsen sensitive skin conditions. To tackle this problem, numerous products have …

In Vitro Cytoprotective Study of Sunscreen Cream X against Pollution Models

Edition

-

ISBN/ISSN

-

Collation

-

Series Title

-

Call Number

PHA 22-002

ANTIOXIDANT POTENTIAL OF CALOPHYLLUM INOPHYLLUM EXTRACT FOR ATOPIC DERMATITIS…

Atopic dermatitis is a multifactorial chronic skin inflammatory disease characterized by acute flare-ups and exacerbations, chronic eczematous skin lesions on dry skin, as well as intensive pruritus. It affects 10-30% of children and 2-10% of adult worldwide with an early onset. Currently, there has been no treatment that can address this disease completely. This research is aimed to investigat…