In order to address the needs of infants with cow's milk allergy, two formulations of a semi-solid, dairy-free, ready-to-use complementary food were developed. These formulations were created in an attempt to fulfill BPOM regulations and infant recommended dietary allowance values, differing only in their peanut oil to palm rations: formula 1 (30:177) and formula 2 (50:157). Both Formulae were …
Apple (Malus domestica) is the second most popular fruit for processing globally due to its high nutritional value. However, with the increasing health consciousness, consumers are looking for foods and beverages with health-promoting benefits and nutritional value. Thus, the demand for functional foods and beverages with prebiotic properties.
Lipid-based dairy free RUCF is a ready to use complementary food made with local ingredients. The important quality of the RUCF is the nutrient composition and physicochemical properties, especially the oil separation and PV. With the problems encountered with oil separation in previous study about development of lipid-based dairy free RUCF, this study will reformulate the RUCF with adjuste…
The study addressed the global health concern surrounding folate deficiency by proposing the development of folate-enriched natural snacks using osmotic dehydration, due to its potential to fortify fruits with essential vitamins. The study was structured into preliminary and primary studies. In the preliminary study, a variety of fruits were assessed, and guava was selected as the most suit…
The turkey berry was first found in 1899 in Columbia County, Florida, and has since spread to at least nine other nations in the Florida peninsula. Turkey berry (Solanum torvum), a nutrient-rich plant, offers significant medicinal and culinary benefits due to its anti-inflammatory, antioxidant, and antibacterial properties. Despite its health advantages, its consumption is limited by its bit…
Modern food packaging provides a way to make food safe, reliable, shelf-stable and clean. Edible films, composed of biopolymers that biodegrade along with the food they contain, offer a preservation in structural integrity, and prevention in microbial growth as well as moisture loss. Edible films, crafted from abundantly found ingredients like carrageenan, offer a cost-effective and environ…
Utilization of local raw materials such as sago can be an alternative to replace the use of wheat flour in noodle production. However, noodles in general and even sago noodles lack essential nutrients, especially protein and minerals. To address this, fortification processes involving the materials high in protein, anchovies (Stolephorus sp.) and minerals, brown seaweed (Sargassum sp.) are e…
The increasing popularity of pasta is correlated with both modern and busy consumer lifestyles where versatility and convenience become a major key factor in consumer perception and buying decisions. In order to fulfill the market demand, a modern approach to optimize the nutritional value as well as the physical properties of pasta by fortifications has been promoted. One example of the for…
Ochratoxin A (OTA) is a carcinogenic mycotoxin that is widely present in coffee beans and causes public health concern that can widely grow in Indonesia’s temperature. This present study aims to evaluate the OTA contamination level in Robusta coffee beans Indonesia using LC-MS/MS analysis. The age group and consumption rate was determined from the literature as follows: 19-25 years old (h…
As a fruit, apple provides a considerable amount of bioactive compounds, including antioxidant and anti-inflammatory compounds. It is known as rapidly perishable food and is usually processed into apple juice in order to prolong its shelf-life. Conventional apple juice processing utilizes the thermal treatment that may cause the degradation of bioactive compounds. Alternatively, a hurdle of…
A significant amount of seaweed is produced in Thailand. Therefore, the innovation of seaweed must improve the market for harvesters. The hydrocolloid gels in the food industry are becoming more popular due to their ability to improve food quality . Fish cake is a soft, springy processed food made from shredded fish that has been combined with crushed ice and salt. The addition of hydrocoll…
Indonesia is a major coffee producer with government initiatives targeting the increased demand for Arabica coffee (Coffea arabica). However, Indonesia is a tropical country, which is ideal for the growth of Ochratoxin A (OTA) producers like Aspergillus and Penicillium. OTA is a food safety risk due to its potential for nephrotoxicity and carcinogenicity at high exposure levels. There is sti…
Developing Texturized Vegetable Protein (TVP) from alternative sources is crucial in addressing the concerns associated with soy-based TVP. This study explores the potential of rice bran and mung bean as sustainable and nutritious alternatives to soy in TVP production. The samples were formulated to produce TVP with 55% protein based on the materials: soy (S-TVP) as control, soy and rice bra…
The prevalence of celiac disease has increased significantly over the past decades due to people’s growing knowledge and awareness of the disease, as well as recent advances in its diagnostic tests. This causes the rise of gluten-free foods, including gluten-free bakery goods. Out of all gluten-free flours, rice flour has been recognised as the most suitable flour for gluten-free bakery go…
Pasta is a popular option for many consumers in the world wide. Colored pasta is one creative method to draw consumers' visual. Red fruit oil (RFO) is one of the natural colorants available. RFO has low solubility and sensitive to external conditions. An innovative solution to the problem is using encapsulation to convert oil-based components into powder-based ones. This study aims to examin…
Natural colorant is currently preferred over synthetic colorant due to health reasons. Red fruit oil (RFO) extract becomes a potential orange-red natural source. However, limitation in solubility and susceptibility to external conditions is present. Encapsulation by co-crystallization can be utilized to solve the limitations. During the co-crystallization process, xylitol is utilized to repl…
Jelly drinks are semisolid, readytodrink beverages made from hydrocolloids They are popular but typically lack nutrition, therefore, this study developed healthier variants using real fruit extract, like pineapple juice Hydrocolloids are essential for producing a desirable texture in jelly drinks, and quality is preserved during pasteurization by employing both thermal and nonthermal techniq…
Vanilla (Vanilla planifolia) is prized for its unique flavor, typically consumed as vanilla extract, which requires substantial extraction time using volatile ethanol. Natural deep eutectic solvents (NADES), abundant and non-volatile, have shown solvating ability for bioactive compounds. This study examines the yield of phenolics from vanilla beans based on total phenolic content (TPC), usin…
DNA damage is a complex phenomenon arising from both endogenous and exogenous sources, posing threats to genomic stability and necessitating an effective DNA damage response (DDR). A dysfunctional DDR can cause genomic instability, which is defined by a higher frequency of DNA mutations. Genomic instability is a common feature of many cancers, and it can result in oncogenic mutations and tu…
Colorectal cancer is the third place cause of death tumor globally. And its frequent prevalence may be caused by the conventional treatments that has been applied. One of the conventional or commonly used treatments are chemotherapy, one of colorectal cancer common chemotherapy are oxaliplatin. This would create drug-resistant cancer. For this effort in counteracting the resistant caused by …
SARS-CoV-2, the cause of the COVID-19 pandemic, prompted rapid vaccine development. However, emerging variants challenge antibody-mediated protection. Targeting T-cell immunity is promising due to its crucial role in eliminating infected cells and the difficulty of viral evasion via HLA diversity. Despite this potential, there is a lack of HLA studies and SARS-CoV-2 epitope mapping in the I…
Colorectal cancer (CRC) ranks third in cancer incidence and cancer-related mortalities worldwide. The transformation of normal colon and rectal cells to malignant adenocarcinomas due to unrepaired DNA damage which leads to oncogenic mutations. These mutations also increase the frequency of DNA damage, leading to endogenous replication stress (RS). This introduces an opportunity to induce sy…
There have been reports regarding the autoimmunity induced by SARS-CoV-2 in COVID-19 patients, such as: GBS, SLE, multiple sclerosis, demyelinating neuropathies, and orthostatic tachycardia syndrome, narcolepsy, even vaccine-induced. However, the exact mechanism is still unclear. One of possible reason is molecular mimicry, a condition in which the T-cell epitopes come from the virus antige…
COVID-19, caused by the SARS-CoV-2 virus, has resulted in a pandemic with 6.8 million confirmed cases in Indonesia as of December 2023. The high number of cases has necessitated the need for robust and specific diagnostic tools. Despite its effectiveness, the qRT-PCR suggested by the World Health Organization has a number of drawbacks, such as expensive costs, the need for trained personnel …
Red fruit oil (RFO) extract serves as a natural red colorant but exhibits limitations related to solubility and susceptibility to environmental factors such as oxygen, heat, and light-induced degradation. Encapsulation through co-crystallization represents a promising approach to mitigate these challenges. In this context, erythritol is employed instead of sucrose during co-crystallization t…
This research aims to develop an alcohol free craft beer utilizing Momordica charantia, otherwise known as bitter melon, as a hops substitute. This study substitutes hops with 0%, 25%, 50%, 75%, and 100% of bitter melon. The alcohol free beer was prepared by malting, mashing, brewing, fermentation, and incubation, followed by giving heat treatment to the beer separating them into non-heat t…
Plant-based or non-dairy milk substitutes are becoming favored in the growing field of functional beverages driven by factors such as health benefits, allergies, lactose intolerance, and the rise in vegan diets. However, there are challenges to producing oat milk, such as achieving the desirable texture and taste. This study is aimed to have 4 treatments utilizing 2 different kinds of amylas…
Bread is widely favoured food due to simple composition and convenient suitability for daily consumption. One of the main ingredients used to determine the bread quality is yeast. As the Indonesian bread industry has grown, bread is being processed by replacing instant yeast with natural yeast because of increasing consumer interest natural products. Natural yeast is obtained from fermented…
Arak, a traditional Indonesian spirit typically produced from rice or sugarcane, is made by fermenting rice or fruit juice followed by distillation. This research explores using snake fruit (Salacca Zalacca var Pondoh) as an innovative raw material for Arak production, offering a novel flavor profile and creating a niche market. Snake fruit, containing fermentable sugars, presents a cost-eff…
Mycoproteins, that are produced through filamentous fungi fermentation, have gained popularity because of their rich protein content and sustainability as an animal-based protein alternative. However, the cost of the commerciallized mycoprotein exceeds the cost of regular meat. Therefore, scientists are exploring various inexpensive substrates and GRAS fungal strains with high survivability …
This study focuses on the characterization of bacterial communities in Takakura compost specifically applied to Saga plants. Takakura compost, known for its simplicity, cost-effectiveness, and efficacy in producing high-quality compost, utilizes the natural processes of microorganisms to break down organic materials. The research involves the analysis of bacterial communities during the comp…
Bacterial cellulose (BC) is a promising packing material as it is biodegradable, non-toxic, has good mechanical properties, and can form bonds with foreign particles. Meanwhile, P. acidilactici postbiotics (metabolites) have the potential to be a natural food preservative as they contain antimicrobial compounds that are heat- and pH-stable. This research aims to develop a novel antimicrobia…
Compost has an important ecological role in increasing soil fertility, plant growth and sustainable agriculture, especially in recycling organic waste. This research characterizes the role of Plant Growth Promoting Fungi (PGPF) derived from Takakura compost and analyzes the influence of microbial communities on saga plants (Abrus precatorius). Takakura Compost is an alternative because of i…
Psoriasis is a prevalent chronic autoimmune inflammatory skin disease affecting over 125 million individuals globally, posing a significant health challenge. Investigating synthetic compounds featuring the 1,2,3-triazole structure known for their anti-inflammatory effects, this research aimed to evaluate synthetic drug compound candidates for their anti-inflammatory properties. The assessmen…
Hydroponic cultivation has emerged as a cost-effective alternative to traditional soil-based agriculture and may be less susceptible to pests and diseases. They can be set up in controlled environments, making them suitable for year-round production in urban areas with limited land availability. EM4 is a type of fertilizer that can increase agricultural systems' decomposition, composting, a…
Abrus precatorius, colloquially known as the Saga plant, produces various secondary metabolites with valuable pharmaceutical properties such as glycyrrhizin and abrusoside. Methyl jasmonate (MeJA) is a phytohormone known to regulate the expression of the MYC2 transcription factor, which in turn promotes the biosynthesis of secondary metabolites in plants. Understanding the resolution to enh…
Abrus precatorius, known as Saga, is a legume plant belonging to the tropical Asia region that is known for its toxicity. Precedent research has shown that Abrus precatorius leaves and roots have a potential effect on treating various diseases such as cough, bronchitis, hepatitis, and cancer. However, Saga plants are being undervalued in Indonesia due to the lack of knowledge on the benefit…
Wound dressings play a crucial role in promoting efficient wound closure and healing by providing an environment conducive to tissue repair. Traditional wound dressings, such as cellulose-based gauze, often exhibit challenges in adhesion and exudate absorption, necessitating frequent replacements that may cause additional trauma. Biocellulose (BC), derived from bacteria, presents a natural c…
Aquaculture industries are evolving rapidly to meet the escalating global demand for seafood as the human population grows. Enhancing the nutritional quality of feed for aquatic animals, such as fish larvae, is critical for increasing seafood production sustainably. Live feed, particularly copepods (crustacean zooplankton), has emerged as a preferred alternative to conventional synthetic fee…
Pediococcus acidilactici is a gram-positive lactic acid bacteria (LAB) widely used as a probiotic due to its safety, benefits, and ability to survive in the harsh environment of the gastrointestinal (GI) tract. One of the challenges for probiotic species is the presence of bile salt, which can degrade bacterial cell membrane due to its main function in lipid solubilization. Bile salt can als…